Candesartan cilexetil

Name: Candesartan cilexetil
Brand: Vaqora Chemicals
SKU: VQ-021968

About Candesartan cilexetil

Candesartan cilexetil (CAS 145040-37-5) is an impurity of Candesartan offered by Vaqora Chemicals. Formula C33H34N6O6, molecular weight 610.7 g/mol. Alternative names: TCV-116 and candesartan cilexitil.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Danger” with 11 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Candesartan to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Candesartan

View every impurity, metabolite and intermediate we list for Candesartan.

Candesartan impurities

Specifications & identifiers

Chemical identifiers
Product name	Candesartan cilexetil
Catalogue No.	VQ-021968
CAS Number	145040-37-5
IUPAC name	1-cyclohexyloxycarbonyloxyethyl 2-ethoxy-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylate
Molecular formula	C₃₃H₃₄N₆O₆
Molecular weight	610.7 g/mol
Exact mass	610.254
Grade	Reference Standard
HSN code	38229090
InChIKey	GHOSNRCGJFBJIB-UHFFFAOYSA-N
SMILES	CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5)C(=O)OC(C)OC(=O)OC6CCCCC6
PubChem CID	2540

Physical properties
Physical form	Solid
LogP (XLogP3)	7
H-bond donors / acceptors	1 / 10
TPSA	143 Å²
Synonyms	TCV-116, Candesartan 1-(((cyclohexyloxy)carbonyl)oxy)ethyl ester, candesartan cilexitil, Candesartan Celexetil Ester, 1H-Benzimi, Candesartan hexetil, TCY 116, Candesartan cilexetil - Bio-X trade mark

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
H360May damage fertility or the unborn child
H361Suspected of damaging fertility or the unborn child
H362May cause harm to breast-fed children
H373May causes damage to organs through prolonged or repeated exposure
H400Very toxic to aquatic life

Precautionary statements: P203, P260, P261, P263, P264, P264 + P265, P270, P271, P273, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P318, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P391, P403 + P233

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Candesartan cilexetil?

The CAS Registry Number of Candesartan cilexetil is 145040-37-5. It is also known as TCV-116, Candesartan 1-(((cyclohexyloxy)carbonyl)oxy)ethyl ester, candesartan cilexitil.

What is the molecular formula and molecular weight of Candesartan cilexetil?

Candesartan cilexetil has the molecular formula C33H34N6O6 and a molecular weight of 610.7 g/mol. Its IUPAC name is 1-cyclohexyloxycarbonyloxyethyl 2-ethoxy-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylate.

What is Candesartan cilexetil used for?

Candesartan cilexetil is supplied as a characterised reference material related to Candesartan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Candesartan cilexetil can I order?

We supply Candesartan cilexetil in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Candesartan cilexetil?

Yes. Every lot of Candesartan cilexetil is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Candesartan cilexetil be shipped internationally?

Yes. Candesartan cilexetil is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.