(-)-β-D-Dioxolane-5-fluoro Cytidine

Name: (-)-β-D-Dioxolane-5-fluoro Cytidine
Brand: Vaqora Chemicals
SKU: VQ-030469

About (-)-β-D-Dioxolane-5-fluoro Cytidine

Vaqora Chemicals supplies (-)-β-D-Dioxolane-5-fluoro Cytidine, an impurity of Emtricitabine registered under CAS number 145397-26-8. The compound has the formula C8H10FN3O4, corresponding to a molecular weight of 231.18 g/mol. Systematically, it is named 4-amino-5-fluoro-1-[(2S,4S)-2-(hydroxymethyl)-1,3-dioxolan-4-yl]pyrimidin-2-one. Common synonyms include (-)-Beta-D-Dioxolane-5-fluoro Cytidine and 5-Fhmed-cytosine.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Emtricitabine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies (-)-β-D-Dioxolane-5-fluoro Cytidine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Emtricitabine

View every impurity, metabolite and intermediate we list for Emtricitabine.

Emtricitabine impurities

Specifications & identifiers

Chemical identifiers
Product name	(-)-β-D-Dioxolane-5-fluoro Cytidine
Catalogue No.	VQ-030469
CAS Number	145397-26-8
IUPAC name	4-amino-5-fluoro-1-[(2S,4S)-2-(hydroxymethyl)-1,3-dioxolan-4-yl]pyrimidin-2-one
Molecular formula	C₈H₁₀FN₃O₄
Molecular weight	231.18 g/mol
Exact mass	231.0655
Grade	Reference Standard
HSN code	38229090
InChIKey	RJKXXGNCKMQXTH-WDSKDSINSA-N
SMILES	C1[C@H](O[C@H](O1)CO)N2C=C(C(=NC2=O)N)F
PubChem CID	477194

Physical properties
Physical form	Solid
LogP (XLogP3)	-1.9
H-bond donors / acceptors	2 / 5
TPSA	97.4 Å²
Synonyms	(-)-Beta-D-Dioxolane-5-fluoro Cytidine, 5-Fhmed-cytosine, 5-Fluoro-1-(2-(hydroxymethyl)-1,3-dioxolan-4-yl)cytosine, 2(1H)-Pyrimidinone, 4-amino-5-fluoro-1-(2-(hydroxymethyl)-1,3-dioxolan-4-yl)-, (2S-cis)-, 4-amino-5-fluoro-1-((2S,4S)-2-(hydroxymethyl)-1,3-dioxolan-4-yl)pyrimidin-2(1H)-one, 4-amino-5-fluoro-1-[(2s,4s)-2-(hydroxymethyl)-1,3-dioxolan-4-yl]pyrimidin-2(1h)-one, 2(1H)-Pyrimidinone, 4-amino-5-fluoro-1-[(2S,4S)-2-(hydroxymethyl)-1,3-dioxolan-4-yl]-, L-DOFC, L-FDOC, (-)-FDOC, 4-Amino-5-fluoro-1-[(2S,4S)-2-(hydroxymethyl)-1,3-dioxolan-4-yl]-2(1H)-pyrimidinone

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (-)-β-D-Dioxolane-5-fluoro Cytidine?

The CAS Registry Number of (-)-β-D-Dioxolane-5-fluoro Cytidine is 145397-26-8. It is also known as (-)-Beta-D-Dioxolane-5-fluoro Cytidine, 5-Fhmed-cytosine, 5-Fluoro-1-(2-(hydroxymethyl)-1,3-dioxolan-4-yl)cytosine.

What is the molecular formula and molecular weight of (-)-β-D-Dioxolane-5-fluoro Cytidine?

(-)-β-D-Dioxolane-5-fluoro Cytidine has the molecular formula C8H10FN3O4 and a molecular weight of 231.18 g/mol. Its IUPAC name is 4-amino-5-fluoro-1-[(2S,4S)-2-(hydroxymethyl)-1,3-dioxolan-4-yl]pyrimidin-2-one.

What is (-)-β-D-Dioxolane-5-fluoro Cytidine used for?

(-)-β-D-Dioxolane-5-fluoro Cytidine is supplied as a characterised reference material related to Emtricitabine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (-)-β-D-Dioxolane-5-fluoro Cytidine can I order?

We supply (-)-β-D-Dioxolane-5-fluoro Cytidine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (-)-β-D-Dioxolane-5-fluoro Cytidine?

Yes. Every lot of (-)-β-D-Dioxolane-5-fluoro Cytidine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (-)-β-D-Dioxolane-5-fluoro Cytidine be shipped internationally?

Yes. We export (-)-β-D-Dioxolane-5-fluoro Cytidine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.