Lorlatinib Acid Impurity

Name: Lorlatinib Acid Impurity
Brand: Vaqora Chemicals
SKU: VQ-026508

About Lorlatinib Acid Impurity

Lorlatinib Acid Impurity (CAS 1455009-85-4) is an impurity of Lorlatinib offered by Vaqora Chemicals. With the molecular formula C21H21FN6O3, it has a molar mass of 424.4 g/mol. It is also known as Lorlatinib benzoic acid metabolite (m8).

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Lorlatinib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Lorlatinib Acid Impurity in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Lorlatinib

View every impurity, metabolite and intermediate we list for Lorlatinib.

Lorlatinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Lorlatinib Acid Impurity
Catalogue No.	VQ-026508
CAS Number	1455009-85-4
IUPAC name	2-[(1R)-1-[[2-amino-5-[5-cyano-1-methyl-3-(methylaminomethyl)pyrazol-4-yl]-3-pyridinyl]oxy]ethyl]-4-fluorobenzoic acid
Molecular formula	C₂₁H₂₁FN₆O₃
Molecular weight	424.4 g/mol
Exact mass	424.1659
Grade	Reference Standard
HSN code	38229090
InChIKey	IFEPJAKXCDYTOK-LLVKDONJSA-N
SMILES	C[C@H](C1=C(C=CC(=C1)F)C(=O)O)OC2=C(N=CC(=C2)C3=C(N(N=C3CNC)C)C#N)N
PubChem CID	89816280

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.9
H-bond donors / acceptors	3 / 9
TPSA	139 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Lorlatinib Acid Impurity?

The CAS Registry Number of Lorlatinib Acid Impurity is 1455009-85-4. It is also known as Lorlatinib benzoic acid metabolite (m8), Lorlatinib metabolite (lorlatinib benzoic acid metabolite-m8).

What is the molecular formula and molecular weight of Lorlatinib Acid Impurity?

Lorlatinib Acid Impurity has the molecular formula C21H21FN6O3 and a molecular weight of 424.4 g/mol. Its IUPAC name is 2-[(1R)-1-[[2-amino-5-[5-cyano-1-methyl-3-(methylaminomethyl)pyrazol-4-yl]-3-pyridinyl]oxy]ethyl]-4-fluorobenzoic acid.

What is Lorlatinib Acid Impurity used for?

Lorlatinib Acid Impurity is supplied as a characterised reference material related to Lorlatinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Lorlatinib Acid Impurity can I order?

We supply Lorlatinib Acid Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Lorlatinib Acid Impurity?

Yes. Every lot of Lorlatinib Acid Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Lorlatinib Acid Impurity be shipped internationally?

Yes. We export Lorlatinib Acid Impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.