4-[(2,4-Dichloro-5-methoxyphenyl)amino]-7-hyd… 1460227-29-5

Name: 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-7-hydroxy-6-methoxy-3-quinolinecarbonitrile
Brand: Vaqora Chemicals
SKU: VQ-029485

About 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-7-hydroxy-6-methoxy-3-quinolinecarbonitrile

Listed under CAS 1460227-29-5, 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-7-hydroxy-6-methoxy-3-quinolinecarbonitrile is a metabolite or degradation product of Bosutinib available from Vaqora Chemicals. Formula C18H13Cl2N3O3, molecular weight 390.2 g/mol. Its systematic (IUPAC) name is 4-(2,4-dichloro-5-methoxyanilino)-7-hydroxy-6-methoxyquinoline-3-carbonitrile. Alternative names: Des(4-methyl-1-piperazinyl)propyl Bosutinib.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants of Bosutinib, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Bosutinib

View every impurity, metabolite and intermediate we list for Bosutinib.

Bosutinib impurities

Specifications & identifiers

Chemical identifiers
Product name	4-[(2,4-Dichloro-5-methoxyphenyl)amino]-7-hydroxy-6-methoxy-3-quinolinecarbonitrile
Catalogue No.	VQ-029485
CAS Number	1460227-29-5
IUPAC name	4-(2,4-dichloro-5-methoxyanilino)-7-hydroxy-6-methoxyquinoline-3-carbonitrile
Molecular formula	C₁₈H₁₃Cl₂N₃O₃
Molecular weight	390.2 g/mol
Exact mass	389.0334
Grade	Reference Standard
HSN code	38229090
InChIKey	YZDCJNFIBYGWGV-UHFFFAOYSA-N
SMILES	COC1=C(C=C2C(=C1)C(=C(C=N2)C#N)NC3=CC(=C(C=C3Cl)Cl)OC)O
PubChem CID	139026100

Physical properties
Physical form	Solid
LogP (XLogP3)	4.8
H-bond donors / acceptors	2 / 6
TPSA	87.4 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-7-hydroxy-6-methoxy-3-quinolinecarbonitrile?

The CAS Registry Number of 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-7-hydroxy-6-methoxy-3-quinolinecarbonitrile is 1460227-29-5. It is also known as 4-(2,4-Dichloro-5-methoxyphenylamino)-7-hydroxy-6-methoxyquinoline-3-carbonitrile, Des(4-methyl-1-piperazinyl)propyl Bosutinib.

What is the molecular formula and molecular weight of 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-7-hydroxy-6-methoxy-3-quinolinecarbonitrile?

4-[(2,4-Dichloro-5-methoxyphenyl)amino]-7-hydroxy-6-methoxy-3-quinolinecarbonitrile has the molecular formula C18H13Cl2N3O3 and a molecular weight of 390.2 g/mol. Its IUPAC name is 4-(2,4-dichloro-5-methoxyanilino)-7-hydroxy-6-methoxyquinoline-3-carbonitrile.

What is 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-7-hydroxy-6-methoxy-3-quinolinecarbonitrile used for?

4-[(2,4-Dichloro-5-methoxyphenyl)amino]-7-hydroxy-6-methoxy-3-quinolinecarbonitrile is supplied as a characterised reference material related to Bosutinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-7-hydroxy-6-methoxy-3-quinolinecarbonitrile can I order?

We supply 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-7-hydroxy-6-methoxy-3-quinolinecarbonitrile in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-7-hydroxy-6-methoxy-3-quinolinecarbonitrile?

Yes. Every lot of 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-7-hydroxy-6-methoxy-3-quinolinecarbonitrile is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-7-hydroxy-6-methoxy-3-quinolinecarbonitrile be shipped internationally?

Yes. We export 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-7-hydroxy-6-methoxy-3-quinolinecarbonitrile worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.