Keto Pioglitazone (M-III)

About Keto Pioglitazone (M-III)

Keto Pioglitazone (M-III) is a metabolite or degradation product of Pioglitazone carrying the CAS registry number 146062-45-5. The compound has the formula C19H18N2O4S, corresponding to a molecular weight of 370.4 g/mol. The IUPAC name is 5-[[4-[2-(5-acetyl-2-pyridinyl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione. It is also known as Keto Pioglitazone or Pioglitazone M3 Metabolite.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Analytical teams use this compound to identify metabolites and degradants of Pioglitazone, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Keto Pioglitazone (M-III) is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Pioglitazone

View every impurity, metabolite and intermediate we list for Pioglitazone.

Pioglitazone impurities

Specifications & identifiers

Chemical identifiers
Product name	Keto Pioglitazone (M-III)
Catalogue No.	VQ-027508
CAS Number	146062-45-5
IUPAC name	5-[[4-[2-(5-acetyl-2-pyridinyl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
Molecular formula	C₁₉H₁₈N₂O₄S
Molecular weight	370.4 g/mol
Exact mass	370.0987
Grade	Reference Standard
HSN code	38229090
InChIKey	JMLKLMFMQRAJNI-UHFFFAOYSA-N
SMILES	CC(=O)C1=CN=C(C=C1)CCOC2=CC=C(C=C2)CC3C(=O)NC(=O)S3
PubChem CID	5201446

Physical properties
Physical form	Solid
LogP (XLogP3)	2.6
H-bond donors / acceptors	1 / 6
TPSA	111 Å²
Synonyms	Keto Pioglitazone, Pioglitazone M3 Metabolite, Ketopioglitazone, Pioglitazone metabolite M3, 2,4-Thiazolidinedione, 5-((4-(2-(5-acetyl-2-pyridinyl)ethoxy)phenyl)methyl)-, 5-((4-(2-(5-Acetyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione, 2,4-Thiazolidinedione, 5-[[4-[2-(5-acetyl-2-pyridinyl)ethoxy]phenyl]methyl]-, Pioglitazone ketone, 5-(4-(2-(5-Acetylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione, 5-[[4-[2-(5-acetylpyridin-2-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione, 5-({4-[2-(5-acetylpyridin-2-yl)ethoxy]phenyl}methyl)-1,3-thiazolidine-2,4-dione

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Keto Pioglitazone (M-III)?

The CAS Registry Number of Keto Pioglitazone (M-III) is 146062-45-5. It is also known as Keto Pioglitazone, Pioglitazone M3 Metabolite, Ketopioglitazone.

What is the molecular formula and molecular weight of Keto Pioglitazone (M-III)?

Keto Pioglitazone (M-III) has the molecular formula C19H18N2O4S and a molecular weight of 370.4 g/mol. Its IUPAC name is 5-[[4-[2-(5-acetyl-2-pyridinyl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione.

What is Keto Pioglitazone (M-III) used for?

Keto Pioglitazone (M-III) is supplied as a characterised reference material related to Pioglitazone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Keto Pioglitazone (M-III) can I order?

We supply Keto Pioglitazone (M-III) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Keto Pioglitazone (M-III)?

Yes. Every lot of Keto Pioglitazone (M-III) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Keto Pioglitazone (M-III) be shipped internationally?

Yes. We export Keto Pioglitazone (M-III) worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.