Dantrolene Sodium

About Dantrolene Sodium

Dantrolene Sodium is a high-purity reference standard of Dantrolene carrying the CAS registry number 14663-23-1. With the molecular formula C14H9N4NaO5, it has a molar mass of 336.23 g/mol. Systematically, it is named sodium 3-[(E)-[5-(4-nitrophenyl)furan-2-yl]methylideneamino]-2-oxo-4H-imidazol-5-olate. It is also known as Dantrium or Dantamacrin.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Laboratories use this Dantrolene standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Dantrolene

View every impurity, metabolite and intermediate we list for Dantrolene.

Dantrolene impurities

Specifications & identifiers

Chemical identifiers
Product name	Dantrolene Sodium
Catalogue No.	VQ-036515
CAS Number	14663-23-1
IUPAC name	sodium 3-[(E)-[5-(4-nitrophenyl)furan-2-yl]methylideneamino]-2-oxo-4H-imidazol-5-olate
Molecular formula	C₁₄H₉N₄NaO₅
Molecular weight	336.23 g/mol
Exact mass	336.0471
Grade	Reference Standard
HSN code	38229090
InChIKey	KSRLIXGNPXAZHD-HAZZGOGXSA-M
SMILES	C1C(=NC(=O)N1/N=C/C2=CC=C(O2)C3=CC=C(C=C3)[N+](=O)[O-])[O-].[Na+]
PubChem CID	6604100

Physical properties
Physical form	Solid
H-bond donors / acceptors	0 / 6
TPSA	127 Å²
Synonyms	Dantrium, Dantamacrin, Dantrolene sodium anhydrous, Dantrolene Sodium (anhydrous), 1-((5-(p-Nitrophenyl)furfurylidene)amino)hydantoin sodium, 2,4-Imidazolidinedione, 1-(((5-(4-nitrophenyl)-2-furanyl)methylene)amino)-, sodium salt, Dantrolene Sodium Hydrate, dantrolene sodium heptahydrate, Dantrolene sodium salt hemiheptahydrate, Sodium, Dantrolene, Ryanodex Dantrolene Sodium, Dantrolene sodium salt

Safety & hazard information (GHS)

Health hazard

Signal word: Warning

Hazard statements

H341Suspected of causing genetic defects
H351Suspected of causing cancer
H361Suspected of damaging fertility or the unborn child
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P280, P318, P319, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Dantrolene Sodium?

The CAS Registry Number of Dantrolene Sodium is 14663-23-1. It is also known as Dantrium, Dantamacrin, Dantrolene sodium anhydrous.

What is the molecular formula and molecular weight of Dantrolene Sodium?

Dantrolene Sodium has the molecular formula C14H9N4NaO5 and a molecular weight of 336.23 g/mol. Its IUPAC name is sodium 3-[(E)-[5-(4-nitrophenyl)furan-2-yl]methylideneamino]-2-oxo-4H-imidazol-5-olate.

What is Dantrolene Sodium used for?

Dantrolene Sodium is supplied as a characterised reference material related to Dantrolene. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Dantrolene Sodium can I order?

We supply Dantrolene Sodium in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Dantrolene Sodium?

Yes. Every lot of Dantrolene Sodium is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Dantrolene Sodium be shipped internationally?

Yes. Dantrolene Sodium is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.