Rosuvastatin Hydroxymethyl Impurity

Name: Rosuvastatin Hydroxymethyl Impurity
Brand: Vaqora Chemicals
SKU: VQ-033655

About Rosuvastatin Hydroxymethyl Impurity

Rosuvastatin Hydroxymethyl Impurity (CAS 147118-36-3) is a metabolite or degradation product of Rosuvastatin offered by Vaqora Chemicals. The compound has the formula C16H20FN3O3S, corresponding to a molecular weight of 353.4 g/mol. Systematically, it is named N-[4-(4-fluorophenyl)-5-(hydroxymethyl)-6-propan-2-ylpyrimidin-2-yl]-N-methylmethanesulfonamide. Alternative names: Rosuvastatin calcium Z7.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 4 hazard statements. Review the Safety Data Sheet before use.

Analytical teams use this compound to identify metabolites and degradants of Rosuvastatin, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Rosuvastatin Hydroxymethyl Impurity in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Rosuvastatin

View every impurity, metabolite and intermediate we list for Rosuvastatin.

Rosuvastatin impurities

Specifications & identifiers

Chemical identifiers
Product name	Rosuvastatin Hydroxymethyl Impurity
Catalogue No.	VQ-033655
CAS Number	147118-36-3
IUPAC name	N-[4-(4-fluorophenyl)-5-(hydroxymethyl)-6-propan-2-ylpyrimidin-2-yl]-N-methylmethanesulfonamide
Molecular formula	C₁₆H₂₀FN₃O₃S
Molecular weight	353.4 g/mol
Exact mass	353.1209
Grade	Reference Standard
HSN code	38229090
InChIKey	MSDYDUNHTAYBHV-UHFFFAOYSA-N
SMILES	CC(C)C1=NC(=NC(=C1CO)C2=CC=C(C=C2)F)N(C)S(=O)(=O)C
PubChem CID	9819937

Physical properties
Physical form	Solid
LogP (XLogP3)	1.7
H-bond donors / acceptors	1 / 7
TPSA	91.8 Å²
Synonyms	4-(4-Fluorophenyl)-6-isopropyl-2-[(N-methyl-N-methylsufonyl)amino]pyrimidine-5-yl-methanol, 5-(Hydroxymethyl)-4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidine, 4-(4-Fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidine-5-methanol, Rosuvastatin calcium Z7, [4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]methanol, [4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulphonylamino)pyrimidin-5-yl]methanol

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Rosuvastatin Hydroxymethyl Impurity?

The CAS Registry Number of Rosuvastatin Hydroxymethyl Impurity is 147118-36-3. It is also known as 4-(4-Fluorophenyl)-6-isopropyl-2-[(N-methyl-N-methylsufonyl)amino]pyrimidine-5-yl-methanol, 5-(Hydroxymethyl)-4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidine, 4-(4-Fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidine-5-methanol.

What is the molecular formula and molecular weight of Rosuvastatin Hydroxymethyl Impurity?

Rosuvastatin Hydroxymethyl Impurity has the molecular formula C16H20FN3O3S and a molecular weight of 353.4 g/mol. Its IUPAC name is N-[4-(4-fluorophenyl)-5-(hydroxymethyl)-6-propan-2-ylpyrimidin-2-yl]-N-methylmethanesulfonamide.

What is Rosuvastatin Hydroxymethyl Impurity used for?

Rosuvastatin Hydroxymethyl Impurity is supplied as a characterised reference material related to Rosuvastatin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Rosuvastatin Hydroxymethyl Impurity can I order?

We supply Rosuvastatin Hydroxymethyl Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Rosuvastatin Hydroxymethyl Impurity?

Yes. Every lot of Rosuvastatin Hydroxymethyl Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Rosuvastatin Hydroxymethyl Impurity be shipped internationally?

Yes. Rosuvastatin Hydroxymethyl Impurity is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.