(S)-3-((R)-2-((R)-(4-((Tertbutyldimethylsilyl… 1478663-96-5

Name: (S)-3-((R)-2-((R)-(4-((Tertbutyldimethylsilyl)oxy)phenyl)((4fluorophenyl)amino)methyl)-4-(2-(4fluorophenyl)-5,5-dimethyl-1,3-dioxan-2yl)butanoyl)-4-phenyloxazolidin-2-one
Brand: Vaqora Chemicals
SKU: VQ-048327

About (S)-3-((R)-2-((R)-(4-((Tertbutyldimethylsilyl)oxy)phenyl)((4fluorophenyl)amino)methyl)-4-(2-(4fluorophenyl)-5,5-dimethyl-1,3-dioxan-2yl)butanoyl)-4-phenyloxazolidin-2-one

Listed under CAS 1478663-96-5, (S)-3-((R)-2-((R)-(4-((Tertbutyldimethylsilyl)oxy)phenyl)((4fluorophenyl)amino)methyl)-4-(2-(4fluorophenyl)-5,5-dimethyl-1,3-dioxan-2yl)butanoyl)-4-phenyloxazolidin-2-one is a process intermediate or related compound of Ezetimibe available from Vaqora Chemicals. The compound has the formula C44H52F2N2O6Si, corresponding to a molecular weight of 771.0 g/mol.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

It is a process intermediate or related compound in the synthesis of Ezetimibe, useful for route development, impurity fate-and-purge studies and analytical method development. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer (S)-3-((R)-2-((R)-(4-((Tertbutyldimethylsilyl)oxy)phenyl)((4fluorophenyl)amino)methyl)-4-(2-(4fluorophenyl)-5,5-dimethyl-1,3-dioxan-2yl)butanoyl)-4-phenyloxazolidin-2-one in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Ezetimibe

View every impurity, metabolite and intermediate we list for Ezetimibe.

Ezetimibe impurities

Specifications & identifiers

Chemical identifiers
Product name	(S)-3-((R)-2-((R)-(4-((Tertbutyldimethylsilyl)oxy)phenyl)((4fluorophenyl)amino)methyl)-4-(2-(4fluorophenyl)-5,5-dimethyl-1,3-dioxan-2yl)butanoyl)-4-phenyloxazolidin-2-one
Catalogue No.	VQ-048327
CAS Number	1478663-96-5
IUPAC name	(4S)-3-[(2R)-2-[(R)-[4-[tert-butyl(dimethyl)silyl]oxyphenyl]-(4-fluoroanilino)methyl]-4-[2-(4-fluorophenyl)-5,5-dimethyl-1,3-dioxan-2-yl]butanoyl]-4-phenyl-1,3-oxazolidin-2-one
Molecular formula	C₄₄H₅₂F₂N₂O₆Si
Molecular weight	771 g/mol
Exact mass	770.3563
HSN code	2933
InChIKey	ILUMERHNJVSKQE-PHAUOLPESA-N
SMILES	CC1(COC(OC1)(CC[C@H]([C@H](C2=CC=C(C=C2)O[Si](C)(C)C(C)(C)C)NC3=CC=C(C=C3)F)C(=O)N4[C@H](COC4=O)C5=CC=CC=C5)C6=CC=C(C=C6)F)C
PubChem CID	73212059

Physical properties
Physical form	Solid
H-bond donors / acceptors	1 / 9
TPSA	86.3 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (S)-3-((R)-2-((R)-(4-((Tertbutyldimethylsilyl)oxy)phenyl)((4fluorophenyl)amino)methyl)-4-(2-(4fluorophenyl)-5,5-dimethyl-1,3-dioxan-2yl)butanoyl)-4-phenyloxazolidin-2-one?

The CAS Registry Number of (S)-3-((R)-2-((R)-(4-((Tertbutyldimethylsilyl)oxy)phenyl)((4fluorophenyl)amino)methyl)-4-(2-(4fluorophenyl)-5,5-dimethyl-1,3-dioxan-2yl)butanoyl)-4-phenyloxazolidin-2-one is 1478663-96-5.

What is the molecular formula and molecular weight of (S)-3-((R)-2-((R)-(4-((Tertbutyldimethylsilyl)oxy)phenyl)((4fluorophenyl)amino)methyl)-4-(2-(4fluorophenyl)-5,5-dimethyl-1,3-dioxan-2yl)butanoyl)-4-phenyloxazolidin-2-one?

(S)-3-((R)-2-((R)-(4-((Tertbutyldimethylsilyl)oxy)phenyl)((4fluorophenyl)amino)methyl)-4-(2-(4fluorophenyl)-5,5-dimethyl-1,3-dioxan-2yl)butanoyl)-4-phenyloxazolidin-2-one has the molecular formula C44H52F2N2O6Si and a molecular weight of 771 g/mol.

What is (S)-3-((R)-2-((R)-(4-((Tertbutyldimethylsilyl)oxy)phenyl)((4fluorophenyl)amino)methyl)-4-(2-(4fluorophenyl)-5,5-dimethyl-1,3-dioxan-2yl)butanoyl)-4-phenyloxazolidin-2-one used for?

(S)-3-((R)-2-((R)-(4-((Tertbutyldimethylsilyl)oxy)phenyl)((4fluorophenyl)amino)methyl)-4-(2-(4fluorophenyl)-5,5-dimethyl-1,3-dioxan-2yl)butanoyl)-4-phenyloxazolidin-2-one is supplied as a characterised reference material related to Ezetimibe. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (S)-3-((R)-2-((R)-(4-((Tertbutyldimethylsilyl)oxy)phenyl)((4fluorophenyl)amino)methyl)-4-(2-(4fluorophenyl)-5,5-dimethyl-1,3-dioxan-2yl)butanoyl)-4-phenyloxazolidin-2-one can I order?

We supply (S)-3-((R)-2-((R)-(4-((Tertbutyldimethylsilyl)oxy)phenyl)((4fluorophenyl)amino)methyl)-4-(2-(4fluorophenyl)-5,5-dimethyl-1,3-dioxan-2yl)butanoyl)-4-phenyloxazolidin-2-one, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (S)-3-((R)-2-((R)-(4-((Tertbutyldimethylsilyl)oxy)phenyl)((4fluorophenyl)amino)methyl)-4-(2-(4fluorophenyl)-5,5-dimethyl-1,3-dioxan-2yl)butanoyl)-4-phenyloxazolidin-2-one?

Yes. Every lot of (S)-3-((R)-2-((R)-(4-((Tertbutyldimethylsilyl)oxy)phenyl)((4fluorophenyl)amino)methyl)-4-(2-(4fluorophenyl)-5,5-dimethyl-1,3-dioxan-2yl)butanoyl)-4-phenyloxazolidin-2-one is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (S)-3-((R)-2-((R)-(4-((Tertbutyldimethylsilyl)oxy)phenyl)((4fluorophenyl)amino)methyl)-4-(2-(4fluorophenyl)-5,5-dimethyl-1,3-dioxan-2yl)butanoyl)-4-phenyloxazolidin-2-one be shipped internationally?

Yes. We export (S)-3-((R)-2-((R)-(4-((Tertbutyldimethylsilyl)oxy)phenyl)((4fluorophenyl)amino)methyl)-4-(2-(4fluorophenyl)-5,5-dimethyl-1,3-dioxan-2yl)butanoyl)-4-phenyloxazolidin-2-one worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.