Melphalan

Name: Melphalan
Brand: Vaqora Chemicals
SKU: VQ-007566

About Melphalan

Vaqora Chemicals supplies Melphalan, a high-purity reference standard of Melphalan registered under CAS number 148-82-3. Formula C13H18Cl2N2O2, molecular weight 305.2 g/mol. Its systematic (IUPAC) name is (2S)-2-amino-3-[4-[bis(2-chloroethyl)amino]phenyl]propanoic acid. Common synonyms include 4-[Bis(2-chloroethyl)amino]-L-phenylalanine and L-PAM.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

As a reference sample of Melphalan, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Melphalan is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Melphalan

View every impurity, metabolite and intermediate we list for Melphalan.

Melphalan impurities

Specifications & identifiers

Chemical identifiers
Product name	Melphalan
Catalogue No.	VQ-007566
CAS Number	148-82-3
Other CAS	3223-07-2, 27960-54-9, 1559066-79-3
IUPAC name	(2S)-2-amino-3-[4-[bis(2-chloroethyl)amino]phenyl]propanoic acid
Molecular formula	C₁₃H₁₈Cl₂N₂O₂
Molecular weight	305.2 g/mol
Exact mass	304.0745
Grade	Reference Standard
HSN code	38229090
InChIKey	SGDBTWWWUNNDEQ-LBPRGKRZSA-N
SMILES	C1=CC(=CC=C1C[C@@H](C(=O)O)N)N(CCCl)CCCl
PubChem CID	460612

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.5
H-bond donors / acceptors	2 / 4
TPSA	66.6 Å²
Synonyms	4-[Bis(2-chloroethyl)amino]-L-phenylalanine, (S)-2-amino-3-(4-(bis(2-chloroethyl)amino)phenyl)propanoic acid, L-PAM, L-Phenylalanine mustard, L-Sarcolysin, L-Sarcolysine, L-Sarkolysin, Alanine nitrogen mustard, Alkeran, Levofalan, Levofolan, Levopholan

Safety & hazard information (GHS)

Toxic

Health hazard

Signal word: Danger

Hazard statements

H300Fatal if swallowed
H310Fatal in contact with skin
H330Fatal if inhaled
H340May cause genetic defects
H350May cause cancer
H361Suspected of damaging fertility or the unborn child

Precautionary statements: P203, P260, P262, P264, P270, P271, P280, P284, P301 + P316, P302 + P352, P304 + P340, P316, P318, P320, P321, P330, P361 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Melphalan?

The CAS Registry Number of Melphalan is 148-82-3. It is also known as 4-[Bis(2-chloroethyl)amino]-L-phenylalanine, (S)-2-amino-3-(4-(bis(2-chloroethyl)amino)phenyl)propanoic acid, L-PAM.

What is the molecular formula and molecular weight of Melphalan?

Melphalan has the molecular formula C13H18Cl2N2O2 and a molecular weight of 305.2 g/mol. Its IUPAC name is (2S)-2-amino-3-[4-[bis(2-chloroethyl)amino]phenyl]propanoic acid.

What is Melphalan used for?

Melphalan is supplied as a characterised reference material related to Melphalan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Melphalan can I order?

We supply Melphalan in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Melphalan?

Yes. Every lot of Melphalan is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Melphalan be shipped internationally?

Yes. Melphalan is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.