DL-Pyroglutamic acid, 99%

About DL-Pyroglutamic acid, 99%

DL-Pyroglutamic acid is a peptide synthesis reagent carrying the CAS registry number 149-87-1 with a typical assay of 99%. Its molecular formula is C5H7NO3 and its molecular weight is 129.11 g/mol. Systematically, it is named 5-oxopyrrolidine-2-carboxylic acid. It is also known as 2-Pyrrolidone-5-carboxylic acid or 5-Oxo-DL-proline.

The material typically appears as a white powder. Literature values give a melting point of 183-185 °C. Store in a tightly closed container in a cool, dry and well-ventilated place. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Key uses span peptide coupling, solid-phase peptide synthesis, bioconjugation and organic synthesis. Typical end-use sectors are academic and industrial research and diagnostics and biotechnology.

We offer DL-Pyroglutamic acid in 25 g, 100 g, 500 g and 5 kg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Peptide coupling
Solid-phase peptide synthesis
Bioconjugation
Organic synthesis

Industries

Specifications & identifiers

Chemical identifiers
Product name	DL-Pyroglutamic acid, 99%
Catalogue No.	VQ-002384
CAS Number	149-87-1
IUPAC name	5-oxopyrrolidine-2-carboxylic acid
Molecular formula	C₅H₇NO₃
Molecular weight	129.11 g/mol
Exact mass	129.0426
Purity / assay	99%
HSN code	29420090
InChIKey	ODHCTXKNWHHXJC-UHFFFAOYSA-N
SMILES	C1CC(=O)NC1C(=O)O
PubChem CID	499

Physical properties
Physical form	Powder
Appearance	White powder
Melting point	183-185 °C
LogP (XLogP3)	-0.8
H-bond donors / acceptors	2 / 3
TPSA	66.4 Å²
Synonyms	2-Pyrrolidone-5-carboxylic acid, 5-Oxo-DL-proline, DL-Proline, 5-oxo-, DL-2-Pyrrolidone-5-carboxylic acid, dl-pyrrolidonecarboxylic acid, DL-2-Pyrrolidinone-5-carboxylic acid, Pyrrolidone carboxylic acid, 5-Oxo-D-prolin, Pyr-OH, 2-L-Pyrrolidone-5-carboxylicacid, DL-Pidolic acid, DL-5-Oxoproline

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of DL-Pyroglutamic acid, 99%?

The CAS Registry Number of DL-Pyroglutamic acid, 99% is 149-87-1. It is also known as 2-Pyrrolidone-5-carboxylic acid, 5-Oxo-DL-proline, DL-Proline, 5-oxo-.

What is the molecular formula and molecular weight of DL-Pyroglutamic acid, 99%?

DL-Pyroglutamic acid, 99% has the molecular formula C5H7NO3 and a molecular weight of 129.11 g/mol. Its IUPAC name is 5-oxopyrrolidine-2-carboxylic acid.

Which grade and pack sizes of DL-Pyroglutamic acid, 99% can I order?

We supply DL-Pyroglutamic acid, 99% in (99%) grade, in 25 g, 100 g, 500 g, 5 kg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with DL-Pyroglutamic acid, 99%?

Yes. Every lot of DL-Pyroglutamic acid, 99% is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can DL-Pyroglutamic acid, 99% be shipped internationally?

Yes. DL-Pyroglutamic acid, 99% is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.