N-Hydroxy-2-(1-nitrosoimidazol-4-yl)acetamide 149573-80-8

About N-Hydroxy-2-(1-nitrosoimidazol-4-yl)acetamide

N-Hydroxy-2-(1-nitrosoimidazol-4-yl)acetamide is a nitrosamine impurity of Mirabegron carrying the CAS registry number 149573-80-8. The compound has the formula C5H6N4O3, corresponding to a molecular weight of 170.13 g/mol. Alternative names: N-Hydroxy-1-nitroso-1H-imidazole-4-acetamide.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

It is used as a reference standard for trace-level detection and quantitation of nitrosamine impurities by LC-MS/MS or GC-MS, supporting nitrosamine risk assessments for Mirabegron, method validation (AMV) and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, N-Hydroxy-2-(1-nitrosoimidazol-4-yl)acetamide is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Mirabegron

View every impurity, metabolite and intermediate we list for Mirabegron.

Mirabegron impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Hydroxy-2-(1-nitrosoimidazol-4-yl)acetamide
Catalogue No.	VQ-030623
CAS Number	149573-80-8
IUPAC name	N-hydroxy-2-(1-nitrosoimidazol-4-yl)acetamide
Molecular formula	C₅H₆N₄O₃
Molecular weight	170.13 g/mol
Exact mass	170.044
Grade	Reference Standard
HSN code	38229090
InChIKey	KLNNAILPTLKFOO-UHFFFAOYSA-N
SMILES	C1=C(N=CN1N=O)CC(=O)NO
PubChem CID	154639

Physical properties
Physical form	Solid
LogP (XLogP3)	-1.4
H-bond donors / acceptors	2 / 5
TPSA	96.6 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Hydroxy-2-(1-nitrosoimidazol-4-yl)acetamide?

The CAS Registry Number of N-Hydroxy-2-(1-nitrosoimidazol-4-yl)acetamide is 149573-80-8. It is also known as (1-Nitroso-1H-imidazol-4-yl)acetohydroxamic acid, 1H-Imidazole-4-acetamide, N-hydroxy-1-nitroso-, N-Hydroxy-1-nitroso-1H-imidazole-4-acetamide.

What is the molecular formula and molecular weight of N-Hydroxy-2-(1-nitrosoimidazol-4-yl)acetamide?

N-Hydroxy-2-(1-nitrosoimidazol-4-yl)acetamide has the molecular formula C5H6N4O3 and a molecular weight of 170.13 g/mol. Its IUPAC name is N-hydroxy-2-(1-nitrosoimidazol-4-yl)acetamide.

What is N-Hydroxy-2-(1-nitrosoimidazol-4-yl)acetamide used for?

N-Hydroxy-2-(1-nitrosoimidazol-4-yl)acetamide is supplied as a characterised reference material related to Mirabegron. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Hydroxy-2-(1-nitrosoimidazol-4-yl)acetamide can I order?

We supply N-Hydroxy-2-(1-nitrosoimidazol-4-yl)acetamide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Hydroxy-2-(1-nitrosoimidazol-4-yl)acetamide?

Yes. Every lot of N-Hydroxy-2-(1-nitrosoimidazol-4-yl)acetamide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Hydroxy-2-(1-nitrosoimidazol-4-yl)acetamide be shipped internationally?

Yes. We export N-Hydroxy-2-(1-nitrosoimidazol-4-yl)acetamide worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.