4-Hydroxy-3-Nitroquinolin-2(1H)-One

Name: 4-Hydroxy-3-Nitroquinolin-2(1H)-One
Brand: Vaqora Chemicals
SKU: VQ-013111

About 4-Hydroxy-3-Nitroquinolin-2(1H)-One

4-Hydroxy-3-Nitroquinolin-2(1H)-One (CAS 15151-57-2) is a process intermediate or related compound of Imiquimod offered by Vaqora Chemicals. With the molecular formula C9H6N2O4, it has a molar mass of 206.15 g/mol. Systematically, it is named 4-hydroxy-3-nitro-1H-quinolin-2-one. Alternative names: 2,4-Dihydroxy-3-nitroquinoline and 3-Nitro-2,4-quinolinediol.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Process chemists and analysts use it when developing synthetic routes to Imiquimod, tracking process-related impurities and validating analytical methods. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 4-Hydroxy-3-Nitroquinolin-2(1H)-One in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Imiquimod

View every impurity, metabolite and intermediate we list for Imiquimod.

Imiquimod impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Hydroxy-3-Nitroquinolin-2(1H)-One
Catalogue No.	VQ-013111
CAS Number	15151-57-2
IUPAC name	4-hydroxy-3-nitro-1H-quinolin-2-one
Molecular formula	C₉H₆N₂O₄
Molecular weight	206.15 g/mol
Exact mass	206.0328
Grade	Reference Standard
HSN code	2933
InChIKey	SHZUGBYEPDMAPC-UHFFFAOYSA-N
SMILES	C1=CC=C2C(=C1)C(=C(C(=O)N2)[N+](=O)[O-])O
PubChem CID	54680162

Physical properties
Physical form	Solid
LogP (XLogP3)	1.3
H-bond donors / acceptors	2 / 4
TPSA	95.2 Å²
Synonyms	2,4-Dihydroxy-3-nitroquinoline, 3-Nitro-2,4-quinolinediol, 4-hydroxy-3-nitro-2(1H)-quinolinone, 3-nitroquinoline-2,4-diol, 4-hydroxy-3-nitro-1,2-dihydroquinolin-2-one, 2(1H)-Quinolinone,4-hydroxy-3-nitro-, 2-hydroxy-3-nitro-1H-quinolin-4-one, 4-Hydroxy-3-nitrocarbostyril, 4-hydroxy-3-nitro-2-quinolone, CS-B0977, 4-hydroxy-3-nitro-2(I H)-quinolinone, 3-Nitro4-hydroxy-1,2-dihydroquinolin-2-one

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Hydroxy-3-Nitroquinolin-2(1H)-One?

The CAS Registry Number of 4-Hydroxy-3-Nitroquinolin-2(1H)-One is 15151-57-2. It is also known as 2,4-Dihydroxy-3-nitroquinoline, 3-Nitro-2,4-quinolinediol, 4-hydroxy-3-nitro-2(1H)-quinolinone.

What is the molecular formula and molecular weight of 4-Hydroxy-3-Nitroquinolin-2(1H)-One?

4-Hydroxy-3-Nitroquinolin-2(1H)-One has the molecular formula C9H6N2O4 and a molecular weight of 206.15 g/mol. Its IUPAC name is 4-hydroxy-3-nitro-1H-quinolin-2-one.

What is 4-Hydroxy-3-Nitroquinolin-2(1H)-One used for?

4-Hydroxy-3-Nitroquinolin-2(1H)-One is supplied as a characterised reference material related to Imiquimod. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Hydroxy-3-Nitroquinolin-2(1H)-One can I order?

We supply 4-Hydroxy-3-Nitroquinolin-2(1H)-One in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Hydroxy-3-Nitroquinolin-2(1H)-One?

Yes. Every lot of 4-Hydroxy-3-Nitroquinolin-2(1H)-One is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Hydroxy-3-Nitroquinolin-2(1H)-One be shipped internationally?

Yes. 4-Hydroxy-3-Nitroquinolin-2(1H)-One is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.