ent-Efavirenz

Name: ent-Efavirenz
Brand: Vaqora Chemicals
SKU: VQ-022492

About ent-Efavirenz

Listed under CAS 154801-74-8, ent-Efavirenz is an impurity of Efavirenz available from Vaqora Chemicals. Its molecular formula is C14H9ClF3NO2 and its molecular weight is 315.67 g/mol. The IUPAC name is (4R)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one. Common synonyms include Efavirenz Enantiomer and Efavirenz, (R)-.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Efavirenz to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer ent-Efavirenz in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Efavirenz

View every impurity, metabolite and intermediate we list for Efavirenz.

Efavirenz impurities

Specifications & identifiers

Chemical identifiers
Product name	ent-Efavirenz
Catalogue No.	VQ-022492
CAS Number	154801-74-8
IUPAC name	(4R)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one
Molecular formula	C₁₄H₉ClF₃NO₂
Molecular weight	315.67 g/mol
Exact mass	315.0274
Grade	Reference Standard
HSN code	38229090
InChIKey	XPOQHMRABVBWPR-CYBMUJFWSA-N
SMILES	C1CC1C#C[C@@]2(C3=C(C=CC(=C3)Cl)NC(=O)O2)C(F)(F)F
PubChem CID	477099

Physical properties
Physical form	Solid
LogP (XLogP3)	4
H-bond donors / acceptors	1 / 5
TPSA	38.3 Å²
Synonyms	Efavirenz Enantiomer, Efavirenz, (R)-, (R)-efavirenz, R-Isomer of Efavirenz, (R)-6-chloro-4-(cyclopropylethynyl)-4-(trifluoromethyl)-1H-benzo[d][1,3]oxazin-2(4H)-one

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of ent-Efavirenz?

The CAS Registry Number of ent-Efavirenz is 154801-74-8. It is also known as Efavirenz Enantiomer, Efavirenz, (R)-, (R)-efavirenz.

What is the molecular formula and molecular weight of ent-Efavirenz?

ent-Efavirenz has the molecular formula C14H9ClF3NO2 and a molecular weight of 315.67 g/mol. Its IUPAC name is (4R)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one.

What is ent-Efavirenz used for?

ent-Efavirenz is supplied as a characterised reference material related to Efavirenz. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of ent-Efavirenz can I order?

We supply ent-Efavirenz in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with ent-Efavirenz?

Yes. Every lot of ent-Efavirenz is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can ent-Efavirenz be shipped internationally?

Yes. We export ent-Efavirenz worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.