4-Amino-2-chloro-5-fluoropyrimidine

Name: 4-Amino-2-chloro-5-fluoropyrimidine
Brand: Vaqora Chemicals
SKU: VQ-030776

About 4-Amino-2-chloro-5-fluoropyrimidine

Vaqora Chemicals supplies 4-Amino-2-chloro-5-fluoropyrimidine, an impurity of Flucytosine registered under CAS number 155-10-2. With the molecular formula C4H3ClFN3, it has a molar mass of 147.54 g/mol. Systematically, it is named 2-chloro-5-fluoropyrimidin-4-amine. It is also known as 2-Chloro-4-amino-5-fluoropyrimidine or 4-Pyrimidinamine, 2-chloro-5-fluoro-.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Flucytosine, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 4-Amino-2-chloro-5-fluoropyrimidine is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Flucytosine

View every impurity, metabolite and intermediate we list for Flucytosine.

Flucytosine impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Amino-2-chloro-5-fluoropyrimidine
Catalogue No.	VQ-030776
CAS Number	155-10-2
IUPAC name	2-chloro-5-fluoropyrimidin-4-amine
Molecular formula	C₄H₃ClFN₃
Molecular weight	147.54 g/mol
Exact mass	147
Grade	Reference Standard
HSN code	38229090
InChIKey	SLQAJWTZUXJPNY-UHFFFAOYSA-N
SMILES	C1=C(C(=NC(=N1)Cl)N)F
PubChem CID	254372

Physical properties
Physical form	Solid
LogP (XLogP3)	0.9
H-bond donors / acceptors	1 / 4
TPSA	51.8 Å²
Synonyms	2-Chloro-4-amino-5-fluoropyrimidine, 4-Pyrimidinamine, 2-chloro-5-fluoro-, 2-chloro-5-fluoro-pyrimidin-4-amine, 2-Chloro-5-fluoro-pyrimidin-4-ylamine, 2-Chlor-4-amino-5-fluorpyrimidin, 2-chloro-5-fluoropyrimidine-4-ylamine, 2-chloro-5-fluoro-4-aminopyrimidine, 2-chloro-5-fluoropyrimidin-4-ylamine, 2-chloro-5-luoropyrimidin-4-amine

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Amino-2-chloro-5-fluoropyrimidine?

The CAS Registry Number of 4-Amino-2-chloro-5-fluoropyrimidine is 155-10-2. It is also known as 2-Chloro-4-amino-5-fluoropyrimidine, 4-Pyrimidinamine, 2-chloro-5-fluoro-, 2-chloro-5-fluoro-pyrimidin-4-amine.

What is the molecular formula and molecular weight of 4-Amino-2-chloro-5-fluoropyrimidine?

4-Amino-2-chloro-5-fluoropyrimidine has the molecular formula C4H3ClFN3 and a molecular weight of 147.54 g/mol. Its IUPAC name is 2-chloro-5-fluoropyrimidin-4-amine.

What is 4-Amino-2-chloro-5-fluoropyrimidine used for?

4-Amino-2-chloro-5-fluoropyrimidine is supplied as a characterised reference material related to Flucytosine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Amino-2-chloro-5-fluoropyrimidine can I order?

We supply 4-Amino-2-chloro-5-fluoropyrimidine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Amino-2-chloro-5-fluoropyrimidine?

Yes. Every lot of 4-Amino-2-chloro-5-fluoropyrimidine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Amino-2-chloro-5-fluoropyrimidine be shipped internationally?

Yes. 4-Amino-2-chloro-5-fluoropyrimidine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.