Rac-Cotinine

Name: Rac-Cotinine
Brand: Vaqora Chemicals
SKU: VQ-049229

About Rac-Cotinine

Vaqora Chemicals supplies Rac-Cotinine, a process intermediate or related compound of Nicotine Hemisulfate registered under CAS number 15569-85-4. Its molecular formula is C10H12N2O and its molecular weight is 176.21 g/mol. The IUPAC name is 1-methyl-5-pyridin-3-ylpyrrolidin-2-one. Alternative names: (+-)-Cotinine and 2-Pyrrolidinone, 1-methyl-5-(3-pyridinyl)-.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

Process chemists and analysts use it when developing synthetic routes to Nicotine Hemisulfate, tracking process-related impurities and validating analytical methods. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Rac-Cotinine in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Nicotine Hemisulfate

View every impurity, metabolite and intermediate we list for Nicotine Hemisulfate.

Nicotine Hemisulfate impurities

Specifications & identifiers

Chemical identifiers
Product name	Rac-Cotinine
Catalogue No.	VQ-049229
CAS Number	15569-85-4
IUPAC name	1-methyl-5-pyridin-3-ylpyrrolidin-2-one
Molecular formula	C₁₀H₁₂N₂O
Molecular weight	176.21 g/mol
Exact mass	176.095
HSN code	2933
InChIKey	UIKROCXWUNQSPJ-UHFFFAOYSA-N
SMILES	CN1C(CCC1=O)C2=CN=CC=C2
PubChem CID	408

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.3
H-bond donors / acceptors	0 / 2
TPSA	33.2 Å²
Synonyms	(+-)-Cotinine, 2-Pyrrolidinone, 1-methyl-5-(3-pyridinyl)-, (+/-)-Cotinine, (S)-1-Methyl-5-(3-pyridyl)-2-pyrrolidinone, 1-Methyl-5-(3-pyridyl)pyrrolidin-2-one

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation

Precautionary statements: P264, P264 + P265, P270, P280, P301 + P317, P302 + P352, P305 + P351 + P338, P321, P330, P332 + P317, P337 + P317, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Rac-Cotinine?

The CAS Registry Number of Rac-Cotinine is 15569-85-4. It is also known as (+-)-Cotinine, 2-Pyrrolidinone, 1-methyl-5-(3-pyridinyl)-, (+/-)-Cotinine.

What is the molecular formula and molecular weight of Rac-Cotinine?

Rac-Cotinine has the molecular formula C10H12N2O and a molecular weight of 176.21 g/mol. Its IUPAC name is 1-methyl-5-pyridin-3-ylpyrrolidin-2-one.

What is Rac-Cotinine used for?

Rac-Cotinine is supplied as a characterised reference material related to Nicotine Hemisulfate. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Rac-Cotinine can I order?

We supply Rac-Cotinine, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Rac-Cotinine?

Yes. Every lot of Rac-Cotinine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Rac-Cotinine be shipped internationally?

Yes. Rac-Cotinine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.