2-((R)-2-Benzyl-3-((3S,4S)-4-(3-hydroxyphenyl… 156130-44-8

About 2-((R)-2-Benzyl-3-((3S,4S)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanamido)acetic Acid

2-((R)-2-Benzyl-3-((3S,4S)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanamido)acetic Acid is a metabolite or degradation product of Alvimopan carrying the CAS registry number 156130-44-8. Its molecular formula is C25H32N2O4 and its molecular weight is 424.5 g/mol. Systematically, it is named 2-[[(2R)-2-benzyl-3-[(3S,4S)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]propanoyl]amino]acetic acid. Common synonyms include ent-Alvimopan and (2R,3S,4S)-Alvimopan.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Alvimopan, as well as in QC testing and ANDA/DMF documentation. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Alvimopan

View every impurity, metabolite and intermediate we list for Alvimopan.

Alvimopan impurities

Specifications & identifiers

Chemical identifiers
Product name	2-((R)-2-Benzyl-3-((3S,4S)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanamido)acetic Acid
Catalogue No.	VQ-021526
CAS Number	156130-44-8
IUPAC name	2-[[(2R)-2-benzyl-3-[(3S,4S)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]propanoyl]amino]acetic acid
Molecular formula	C₂₅H₃₂N₂O₄
Molecular weight	424.5 g/mol
Exact mass	424.2362
Grade	Reference Standard
HSN code	38229090
InChIKey	UPNUIXSCZBYVBB-BSWQBHCVSA-N
SMILES	C[C@@H]1CN(CC[C@]1(C)C2=CC(=CC=C2)O)C[C@@H](CC3=CC=CC=C3)C(=O)NCC(=O)O
PubChem CID	101669948

Physical properties
Physical form	Solid
LogP (XLogP3)	1.7
H-bond donors / acceptors	3 / 5
TPSA	89.9 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-((R)-2-Benzyl-3-((3S,4S)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanamido)acetic Acid?

The CAS Registry Number of 2-((R)-2-Benzyl-3-((3S,4S)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanamido)acetic Acid is 156130-44-8. It is also known as ent-Alvimopan, (2R,3S,4S)-Alvimopan, Alvimopan (2R, 3S, 4S)-Isomer.

What is the molecular formula and molecular weight of 2-((R)-2-Benzyl-3-((3S,4S)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanamido)acetic Acid?

2-((R)-2-Benzyl-3-((3S,4S)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanamido)acetic Acid has the molecular formula C25H32N2O4 and a molecular weight of 424.5 g/mol. Its IUPAC name is 2-[[(2R)-2-benzyl-3-[(3S,4S)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]propanoyl]amino]acetic acid.

What is 2-((R)-2-Benzyl-3-((3S,4S)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanamido)acetic Acid used for?

2-((R)-2-Benzyl-3-((3S,4S)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanamido)acetic Acid is supplied as a characterised reference material related to Alvimopan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-((R)-2-Benzyl-3-((3S,4S)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanamido)acetic Acid can I order?

We supply 2-((R)-2-Benzyl-3-((3S,4S)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanamido)acetic Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-((R)-2-Benzyl-3-((3S,4S)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanamido)acetic Acid?

Yes. Every lot of 2-((R)-2-Benzyl-3-((3S,4S)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanamido)acetic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-((R)-2-Benzyl-3-((3S,4S)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanamido)acetic Acid be shipped internationally?

Yes. We export 2-((R)-2-Benzyl-3-((3S,4S)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanamido)acetic Acid worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.