N-Desmethyl Tamoxifen Hydrochloride

About N-Desmethyl Tamoxifen Hydrochloride

N-Desmethyl Tamoxifen Hydrochloride is a metabolite or degradation product of Tamoxifen carrying the CAS registry number 15917-65-4. With the molecular formula C25H28ClNO, it has a molar mass of 393.9 g/mol. Alternative names: N-Desmethyltamoxifen HCl and N-Demethyltamoxifen Hydrochlorid.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Danger” with 4 hazard statements. Review the Safety Data Sheet before use.

Analytical teams use this compound to identify metabolites and degradants of Tamoxifen, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, N-Desmethyl Tamoxifen Hydrochloride is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Tamoxifen

View every impurity, metabolite and intermediate we list for Tamoxifen.

Tamoxifen impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Desmethyl Tamoxifen Hydrochloride
Catalogue No.	VQ-028193
CAS Number	15917-65-4
IUPAC name	2-[4-[(Z)-1,2-diphenylbut-1-enyl]phenoxy]-N-methylethanamine;hydrochloride
Molecular formula	C₂₅H₂₈ClNO
Molecular weight	393.9 g/mol
Exact mass	393.1859
Grade	Reference Standard
HSN code	38229090
InChIKey	GMLHJWZEYLTNJW-BJFQDICYSA-N
SMILES	CC/C(=C(\C1=CC=CC=C1)/C2=CC=C(C=C2)OCCNC)/C3=CC=CC=C3.Cl
PubChem CID	24200424

Physical properties
Physical form	Solid
H-bond donors / acceptors	2 / 2
TPSA	21.3 Å²
Synonyms	N-Desmethyltamoxifen HCl, Ethanamine, 2-[4-[(1Z)-1,2-diphenyl-1-buten-1-yl]phenoxy]-N-methyl-, hydrochloride (1:1), (Z)-2-(p-(1,2-Diphenyl-1-butenyl)phenoxy)-N-methylethylamine, (Z)-2-(4-(1,2-Diphenylbut-1-en-1-yl)phenoxy)-N-methylethanamine hydrochloride, 2-[4-[(Z)-1,2-Diphenylbut-1-enyl]phenoxy]-N-methylethanamine Hydrochloride, (Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N-methylethanamine Hydrochloride, N-Demethyltamoxifen Hydrochlorid, (Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N-methylethanamine, 2-[4-[(1Z)-1,2-Diphenyl-1-buten-1-yl]phenoxy]-N-methylethanamine HCl

Safety & hazard information (GHS)

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H350May cause cancer
H360May damage fertility or the unborn child
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P203, P273, P280, P318, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Desmethyl Tamoxifen Hydrochloride?

The CAS Registry Number of N-Desmethyl Tamoxifen Hydrochloride is 15917-65-4. It is also known as N-Desmethyltamoxifen HCl, Ethanamine, 2-[4-[(1Z)-1,2-diphenyl-1-buten-1-yl]phenoxy]-N-methyl-, hydrochloride (1:1), (Z)-2-(p-(1,2-Diphenyl-1-butenyl)phenoxy)-N-methylethylamine.

What is the molecular formula and molecular weight of N-Desmethyl Tamoxifen Hydrochloride?

N-Desmethyl Tamoxifen Hydrochloride has the molecular formula C25H28ClNO and a molecular weight of 393.9 g/mol.

What is N-Desmethyl Tamoxifen Hydrochloride used for?

N-Desmethyl Tamoxifen Hydrochloride is supplied as a characterised reference material related to Tamoxifen. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Desmethyl Tamoxifen Hydrochloride can I order?

We supply N-Desmethyl Tamoxifen Hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Desmethyl Tamoxifen Hydrochloride?

Yes. Every lot of N-Desmethyl Tamoxifen Hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Desmethyl Tamoxifen Hydrochloride be shipped internationally?

Yes. N-Desmethyl Tamoxifen Hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.