1-N-Boc-4-Methylenepiperidine

Name: 1-N-Boc-4-Methylenepiperidine
Brand: Vaqora Chemicals
SKU: VQ-027277

About 1-N-Boc-4-Methylenepiperidine

1-N-Boc-4-Methylenepiperidine is an impurity of Efinaconazole carrying the CAS registry number 159635-49-1. Its molecular formula is C11H19NO2 and its molecular weight is 197.27 g/mol. The IUPAC name is tert-butyl 4-methylidenepiperidine-1-carboxylate. Common synonyms include N-Boc-4-methylenepiperidine and N-BOC-4-Methylene Piperidine.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Efinaconazole, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 1-N-Boc-4-Methylenepiperidine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Efinaconazole

View every impurity, metabolite and intermediate we list for Efinaconazole.

Efinaconazole impurities

Specifications & identifiers

Chemical identifiers
Product name	1-N-Boc-4-Methylenepiperidine
Catalogue No.	VQ-027277
CAS Number	159635-49-1
IUPAC name	tert-butyl 4-methylidenepiperidine-1-carboxylate
Molecular formula	C₁₁H₁₉NO₂
Molecular weight	197.27 g/mol
Exact mass	197.1416
Grade	Reference Standard
HSN code	38229090
InChIKey	PDTZMULNKGUIEJ-UHFFFAOYSA-N
SMILES	CC(C)(C)OC(=O)N1CCC(=C)CC1
PubChem CID	2756808

Physical properties
Physical form	Solid
LogP (XLogP3)	1.9
H-bond donors / acceptors	0 / 2
TPSA	29.5 Å²
Synonyms	N-Boc-4-methylenepiperidine, N-BOC-4-Methylene Piperidine, 1-boc-4-methylenepiperidine, tert-butyl 4-methylenepiperidine-1-carboxylate, 1-tert-Butoxycarbonyl-4-methylenepiperidine, 4-methylenepiperidine-1-carboxylic acid tert-butyl ester, tert-butyl 4-methylenepiperidinecarboxylate, 4-methylene-piperidine-1-carboxylic acid tert-butyl ester, boc-4-methylenepiperidine, 1-Boc-4-methylene piperidine, 1-Boc-4-(methylene)piperidine

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1-N-Boc-4-Methylenepiperidine?

The CAS Registry Number of 1-N-Boc-4-Methylenepiperidine is 159635-49-1. It is also known as N-Boc-4-methylenepiperidine, N-BOC-4-Methylene Piperidine, 1-boc-4-methylenepiperidine.

What is the molecular formula and molecular weight of 1-N-Boc-4-Methylenepiperidine?

1-N-Boc-4-Methylenepiperidine has the molecular formula C11H19NO2 and a molecular weight of 197.27 g/mol. Its IUPAC name is tert-butyl 4-methylidenepiperidine-1-carboxylate.

What is 1-N-Boc-4-Methylenepiperidine used for?

1-N-Boc-4-Methylenepiperidine is supplied as a characterised reference material related to Efinaconazole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1-N-Boc-4-Methylenepiperidine can I order?

We supply 1-N-Boc-4-Methylenepiperidine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1-N-Boc-4-Methylenepiperidine?

Yes. Every lot of 1-N-Boc-4-Methylenepiperidine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1-N-Boc-4-Methylenepiperidine be shipped internationally?

Yes. 1-N-Boc-4-Methylenepiperidine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.