3,6-Methylene-2,5-piperazinedione

Name: 3,6-Methylene-2,5-piperazinedione
Brand: Vaqora Chemicals
SKU: VQ-036474

About 3,6-Methylene-2,5-piperazinedione

3,6-Methylene-2,5-piperazinedione (CAS 15996-22-2) is an impurity of Cycloserine offered by Vaqora Chemicals. With the molecular formula C6H6N2O2, it has a molar mass of 138.12 g/mol. Its systematic (IUPAC) name is 3,6-dimethylidenepiperazine-2,5-dione. It is also known as 2,5-dimethylene-3,6-diketopiperazine or 2,5-Piperazinedione, 3,6-dimethylene-.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 4 hazard statements. Review the Safety Data Sheet before use.

This Cycloserine impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Cycloserine

View every impurity, metabolite and intermediate we list for Cycloserine.

Cycloserine impurities

Specifications & identifiers

Chemical identifiers
Product name	3,6-Methylene-2,5-piperazinedione
Catalogue No.	VQ-036474
CAS Number	15996-22-2
IUPAC name	3,6-dimethylidenepiperazine-2,5-dione
Molecular formula	C₆H₆N₂O₂
Molecular weight	138.12 g/mol
Exact mass	138.0429
Grade	Reference Standard
HSN code	38229090
InChIKey	UKQPHICLKVWLEU-UHFFFAOYSA-N
SMILES	C=C1C(=O)NC(=C)C(=O)N1
PubChem CID	72670

Physical properties
Physical form	Solid
H-bond donors / acceptors	2 / 2
TPSA	58.2 Å²
Synonyms	2,5-dimethylene-3,6-diketopiperazine, 2,5-Piperazinedione, 3,6-dimethylene-, 3,6-dimethylene-2,5-piperazinedione, 2,5-Piperazinedione, 3,6-bis(methylene)-, 3,6-dimethylenepiperazine-2,5-dione, 2,5-Piperazinedione,3,6-bis(methylene)-, 3,6-Bis(methylene)piperazine-2,5-dione

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 3,6-Methylene-2,5-piperazinedione?

The CAS Registry Number of 3,6-Methylene-2,5-piperazinedione is 15996-22-2. It is also known as 2,5-dimethylene-3,6-diketopiperazine, 2,5-Piperazinedione, 3,6-dimethylene-, 3,6-dimethylene-2,5-piperazinedione.

What is the molecular formula and molecular weight of 3,6-Methylene-2,5-piperazinedione?

3,6-Methylene-2,5-piperazinedione has the molecular formula C6H6N2O2 and a molecular weight of 138.12 g/mol. Its IUPAC name is 3,6-dimethylidenepiperazine-2,5-dione.

What is 3,6-Methylene-2,5-piperazinedione used for?

3,6-Methylene-2,5-piperazinedione is supplied as a characterised reference material related to Cycloserine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3,6-Methylene-2,5-piperazinedione can I order?

We supply 3,6-Methylene-2,5-piperazinedione in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3,6-Methylene-2,5-piperazinedione?

Yes. Every lot of 3,6-Methylene-2,5-piperazinedione is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3,6-Methylene-2,5-piperazinedione be shipped internationally?

Yes. 3,6-Methylene-2,5-piperazinedione is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.