Ethyl 2-(4-Hydroxyphenyl)-4-methylthiazole-5-… 161797-99-5

Name: Ethyl 2-(4-Hydroxyphenyl)-4-methylthiazole-5-carboxylate
Brand: Vaqora Chemicals
SKU: VQ-030688

About Ethyl 2-(4-Hydroxyphenyl)-4-methylthiazole-5-carboxylate

Ethyl 2-(4-Hydroxyphenyl)-4-methylthiazole-5-carboxylate is a metabolite or degradation product of Febuxostat carrying the CAS registry number 161797-99-5. Its molecular formula is C13H13NO3S and its molecular weight is 263.31 g/mol. Systematically, it is named ethyl 2-(4-hydroxyphenyl)-4-methyl-1,3-thiazole-5-carboxylate.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Analytical teams use this compound to identify metabolites and degradants of Febuxostat, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Ethyl 2-(4-Hydroxyphenyl)-4-methylthiazole-5-carboxylate in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Febuxostat

View every impurity, metabolite and intermediate we list for Febuxostat.

Febuxostat impurities

Specifications & identifiers

Chemical identifiers
Product name	Ethyl 2-(4-Hydroxyphenyl)-4-methylthiazole-5-carboxylate
Catalogue No.	VQ-030688
CAS Number	161797-99-5
IUPAC name	ethyl 2-(4-hydroxyphenyl)-4-methyl-1,3-thiazole-5-carboxylate
Molecular formula	C₁₃H₁₃NO₃S
Molecular weight	263.31 g/mol
Exact mass	263.0616
Grade	Reference Standard
HSN code	38229090
InChIKey	LOCYSKNNFCGDTR-UHFFFAOYSA-N
SMILES	CCOC(=O)C1=C(N=C(S1)C2=CC=C(C=C2)O)C
PubChem CID	135509402

Physical properties
Physical form	Solid
LogP (XLogP3)	3.2
H-bond donors / acceptors	1 / 5
TPSA	87.7 Å²
Synonyms	5-Thiazolecarboxylic acid, 2-(4-hydroxyphenyl)-4-methyl-, ethyl ester, 2-(4-Hydroxyphenyl)-4-methyl-thiazole-5-carboxylic acid ethyl ester, 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylic acid ethyl ester, ethyl 4-methyl-2-(4-oxocyclohexa-2,5-dien-1-ylidene)-3H-1,3-thiazole-5-carboxylate, Ethyl 2-(4-hydroxyphenyl)-4-methyl-5-thiazolecarboxylate, Ethyl 2-(4-Hydroxyphenyl)-4-Methyl-5-Thiazol Carboxylate, 4-Hydroxy-phenyl-4-methyl-thiazole-5-carboxylic acid ethyl ester, 2-(4-hydroxy-phenyl)-4-methyl-thiazole-5-carboxylic acid ethyl ester, Ethyl 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate, AldrichCPR

Safety & hazard information (GHS)

Corrosive

Signal word: Danger

Hazard statements

H318Causes serious eye damage

Precautionary statements: P264 + P265, P280, P305 + P354 + P338, P317

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ethyl 2-(4-Hydroxyphenyl)-4-methylthiazole-5-carboxylate?

The CAS Registry Number of Ethyl 2-(4-Hydroxyphenyl)-4-methylthiazole-5-carboxylate is 161797-99-5. It is also known as 5-Thiazolecarboxylic acid, 2-(4-hydroxyphenyl)-4-methyl-, ethyl ester, 2-(4-Hydroxyphenyl)-4-methyl-thiazole-5-carboxylic acid ethyl ester, 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylic acid ethyl ester.

What is the molecular formula and molecular weight of Ethyl 2-(4-Hydroxyphenyl)-4-methylthiazole-5-carboxylate?

Ethyl 2-(4-Hydroxyphenyl)-4-methylthiazole-5-carboxylate has the molecular formula C13H13NO3S and a molecular weight of 263.31 g/mol. Its IUPAC name is ethyl 2-(4-hydroxyphenyl)-4-methyl-1,3-thiazole-5-carboxylate.

What is Ethyl 2-(4-Hydroxyphenyl)-4-methylthiazole-5-carboxylate used for?

Ethyl 2-(4-Hydroxyphenyl)-4-methylthiazole-5-carboxylate is supplied as a characterised reference material related to Febuxostat. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ethyl 2-(4-Hydroxyphenyl)-4-methylthiazole-5-carboxylate can I order?

We supply Ethyl 2-(4-Hydroxyphenyl)-4-methylthiazole-5-carboxylate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ethyl 2-(4-Hydroxyphenyl)-4-methylthiazole-5-carboxylate?

Yes. Every lot of Ethyl 2-(4-Hydroxyphenyl)-4-methylthiazole-5-carboxylate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ethyl 2-(4-Hydroxyphenyl)-4-methylthiazole-5-carboxylate be shipped internationally?

Yes. Ethyl 2-(4-Hydroxyphenyl)-4-methylthiazole-5-carboxylate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.