Ethyl 2-(3-formyl-4-hydroxyphenyl)-4- methylt… 161798-01-2

Name: Ethyl 2-(3-formyl-4-hydroxyphenyl)-4- methylthiazole-5-carboxylate
Brand: Vaqora Chemicals
SKU: VQ-025728

About Ethyl 2-(3-formyl-4-hydroxyphenyl)-4- methylthiazole-5-carboxylate

Ethyl 2-(3-formyl-4-hydroxyphenyl)-4- methylthiazole-5-carboxylate is a metabolite or degradation product of Febuxostat carrying the CAS registry number 161798-01-2. Formula C14H13NO4S, molecular weight 291.32 g/mol. Its systematic (IUPAC) name is ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl-1,3-thiazole-5-carboxylate. It is also known as 5-Thiazoleca.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Febuxostat, as well as in QC testing and ANDA/DMF documentation. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Ethyl 2-(3-formyl-4-hydroxyphenyl)-4- methylthiazole-5-carboxylate in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Febuxostat

View every impurity, metabolite and intermediate we list for Febuxostat.

Febuxostat impurities

Specifications & identifiers

Chemical identifiers
Product name	Ethyl 2-(3-formyl-4-hydroxyphenyl)-4- methylthiazole-5-carboxylate
Catalogue No.	VQ-025728
CAS Number	161798-01-2
IUPAC name	ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl-1,3-thiazole-5-carboxylate
Molecular formula	C₁₄H₁₃NO₄S
Molecular weight	291.32 g/mol
Exact mass	291.0565
Grade	Reference Standard
HSN code	38229090
InChIKey	NJRGQNNSIAFIJC-UHFFFAOYSA-N
SMILES	CCOC(=O)C1=C(N=C(S1)C2=CC(=C(C=C2)O)C=O)C
PubChem CID	135404723

Physical properties
Physical form	Solid
LogP (XLogP3)	3.2
H-bond donors / acceptors	1 / 6
TPSA	105 Å²
Synonyms	5-Thiazolecarboxylic acid, 2-(3-formyl-4-hydroxyphenyl)-4-methyl-, ethyl ester, 2-(3-formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylic acid ethyl ester, 5-Thiazoleca, 2-(3-Formyl-4-hydroxyphenyl)-4-methyl-5-thiazolecarboxylic Acid Ethyl Ester, ethyl-2-(3-formyl-4-hydroxyphenyl)-4-methyl-5-thiazole carboxylate

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ethyl 2-(3-formyl-4-hydroxyphenyl)-4- methylthiazole-5-carboxylate?

The CAS Registry Number of Ethyl 2-(3-formyl-4-hydroxyphenyl)-4- methylthiazole-5-carboxylate is 161798-01-2. It is also known as 5-Thiazolecarboxylic acid, 2-(3-formyl-4-hydroxyphenyl)-4-methyl-, ethyl ester, 2-(3-formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylic acid ethyl ester, 5-Thiazoleca.

What is the molecular formula and molecular weight of Ethyl 2-(3-formyl-4-hydroxyphenyl)-4- methylthiazole-5-carboxylate?

Ethyl 2-(3-formyl-4-hydroxyphenyl)-4- methylthiazole-5-carboxylate has the molecular formula C14H13NO4S and a molecular weight of 291.32 g/mol. Its IUPAC name is ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl-1,3-thiazole-5-carboxylate.

What is Ethyl 2-(3-formyl-4-hydroxyphenyl)-4- methylthiazole-5-carboxylate used for?

Ethyl 2-(3-formyl-4-hydroxyphenyl)-4- methylthiazole-5-carboxylate is supplied as a characterised reference material related to Febuxostat. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ethyl 2-(3-formyl-4-hydroxyphenyl)-4- methylthiazole-5-carboxylate can I order?

We supply Ethyl 2-(3-formyl-4-hydroxyphenyl)-4- methylthiazole-5-carboxylate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ethyl 2-(3-formyl-4-hydroxyphenyl)-4- methylthiazole-5-carboxylate?

Yes. Every lot of Ethyl 2-(3-formyl-4-hydroxyphenyl)-4- methylthiazole-5-carboxylate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ethyl 2-(3-formyl-4-hydroxyphenyl)-4- methylthiazole-5-carboxylate be shipped internationally?

Yes. Ethyl 2-(3-formyl-4-hydroxyphenyl)-4- methylthiazole-5-carboxylate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.