Ezetimibe Open-Ring Acid

Name: Ezetimibe Open-Ring Acid
Brand: Vaqora Chemicals
SKU: VQ-037176

About Ezetimibe Open-Ring Acid

Vaqora Chemicals supplies Ezetimibe Open-Ring Acid, an impurity of Ezetimibe registered under CAS number 1618657-29-6. With the molecular formula C24H23F2NO4, it has a molar mass of 427.4 g/mol. Systematically, it is named (2R,5S)-2-[(S)-(4-fluoroanilino)-(4-hydroxyphenyl)methyl]-5-(4-fluorophenyl)-5-hydroxypentanoic acid.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Ezetimibe to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Ezetimibe Open-Ring Acid in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ezetimibe

View every impurity, metabolite and intermediate we list for Ezetimibe.

Ezetimibe impurities

Specifications & identifiers

Chemical identifiers
Product name	Ezetimibe Open-Ring Acid
Catalogue No.	VQ-037176
CAS Number	1618657-29-6
IUPAC name	(2R,5S)-2-[(S)-(4-fluoroanilino)-(4-hydroxyphenyl)methyl]-5-(4-fluorophenyl)-5-hydroxypentanoic acid
Molecular formula	C₂₄H₂₃F₂NO₄
Molecular weight	427.4 g/mol
Exact mass	427.1595
Grade	Reference Standard
HSN code	38229090
InChIKey	XGNDFEVQHMNNOJ-XPWALMASSA-N
SMILES	C1=CC(=CC=C1[C@H]([C@@H](CC[C@@H](C2=CC=C(C=C2)F)O)C(=O)O)NC3=CC=C(C=C3)F)O
PubChem CID	71316706

Physical properties
Physical form	Solid
LogP (XLogP3)	4.9
H-bond donors / acceptors	4 / 7
TPSA	89.8 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ezetimibe Open-Ring Acid?

The CAS Registry Number of Ezetimibe Open-Ring Acid is 1618657-29-6.

What is the molecular formula and molecular weight of Ezetimibe Open-Ring Acid?

Ezetimibe Open-Ring Acid has the molecular formula C24H23F2NO4 and a molecular weight of 427.4 g/mol. Its IUPAC name is (2R,5S)-2-[(S)-(4-fluoroanilino)-(4-hydroxyphenyl)methyl]-5-(4-fluorophenyl)-5-hydroxypentanoic acid.

What is Ezetimibe Open-Ring Acid used for?

Ezetimibe Open-Ring Acid is supplied as a characterised reference material related to Ezetimibe. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ezetimibe Open-Ring Acid can I order?

We supply Ezetimibe Open-Ring Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ezetimibe Open-Ring Acid?

Yes. Every lot of Ezetimibe Open-Ring Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ezetimibe Open-Ring Acid be shipped internationally?

Yes. We export Ezetimibe Open-Ring Acid worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.