N-Methyl-N-(pyridin-2-yl)nitrous amide

About N-Methyl-N-(pyridin-2-yl)nitrous amide

N-Methyl-N-(pyridin-2-yl)nitrous amide is a nitrosamine impurity standard carrying the CAS registry number 16219-98-0. With the molecular formula C6H7N3O, it has a molar mass of 137.14 g/mol. Alternative names: 2-(Nitrosomethylamino)pyridine and N-Nitroso-N-methyl-2-aminopyridine.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

It is used as a reference standard for trace-level detection and quantitation of nitrosamine impurities by LC-MS/MS or GC-MS, supporting nitrosamine risk assessments, method validation (AMV) and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer N-Methyl-N-(pyridin-2-yl)nitrous amide in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. Stock is available for quick dispatch.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Specifications & identifiers

Chemical identifiers
Product name	N-Methyl-N-(pyridin-2-yl)nitrous amide
Catalogue No.	VQ-006869
CAS Number	16219-98-0
IUPAC name	N-methyl-N-pyridin-2-ylnitrous amide
Molecular formula	C₆H₇N₃O
Molecular weight	137.14 g/mol
Exact mass	137.0589
Grade	Reference Standard
HSN code	38229090
InChIKey	WJDNMDMNPIKDCP-UHFFFAOYSA-N
SMILES	CN(C1=CC=CC=N1)N=O
PubChem CID	146270

Physical properties
Physical form	Solid
LogP (XLogP3)	1.4
H-bond donors / acceptors	0 / 4
TPSA	45.6 Å²
Synonyms	2-(Nitrosomethylamino)pyridine, N-Nitroso-N-methyl-2-aminopyridine, N-Methyl-N-nitroso-2-pyridinamine, 2-Nitrosomethylaminopyridine, 2-Pyridinamine, N-methyl-N-nitroso-, N-methyl-N-nitrosopyridin-2-amine, Pyridine, 2-(methylnitrosamino)-, N-Methyl-N-nitroso-2-aminopyridine, Methyl(pyridin-2-yl)nitrosamine, Pyridine, 2-nitrosomethylamino-, 5-22-14-00723 (Beilstein Handbook Reference), N-nitroso-N-methylamino-pyridine

Safety & hazard information (GHS)

Toxic

Health hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H350May cause cancer

Precautionary statements: P203, P264, P270, P280, P301 + P316, P318, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Methyl-N-(pyridin-2-yl)nitrous amide?

The CAS Registry Number of N-Methyl-N-(pyridin-2-yl)nitrous amide is 16219-98-0. It is also known as 2-(Nitrosomethylamino)pyridine, N-Nitroso-N-methyl-2-aminopyridine, N-Methyl-N-nitroso-2-pyridinamine.

What is the molecular formula and molecular weight of N-Methyl-N-(pyridin-2-yl)nitrous amide?

N-Methyl-N-(pyridin-2-yl)nitrous amide has the molecular formula C6H7N3O and a molecular weight of 137.14 g/mol. Its IUPAC name is N-methyl-N-pyridin-2-ylnitrous amide.

Which grade and pack sizes of N-Methyl-N-(pyridin-2-yl)nitrous amide can I order?

We supply N-Methyl-N-(pyridin-2-yl)nitrous amide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Methyl-N-(pyridin-2-yl)nitrous amide?

Yes. Every lot of N-Methyl-N-(pyridin-2-yl)nitrous amide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Methyl-N-(pyridin-2-yl)nitrous amide be shipped internationally?

Yes. N-Methyl-N-(pyridin-2-yl)nitrous amide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.