1,1'-[Dithiobis(methylene)]biscyclopropaneace… 162515-67-5

About 1,1'-[Dithiobis(methylene)]biscyclopropaneacetic Acid

1,1'-[Dithiobis(methylene)]biscyclopropaneacetic Acid is an impurity of Montelukast carrying the CAS registry number 162515-67-5. Its molecular formula is C12H18O4S2 and its molecular weight is 290.4 g/mol. Systematically, it is named 2-[1-[[[1-(carboxymethyl)cyclopropyl]methyldisulfanyl]methyl]cyclopropyl]acetic acid.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Montelukast to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Montelukast

View every impurity, metabolite and intermediate we list for Montelukast.

Montelukast impurities

Specifications & identifiers

Chemical identifiers
Product name	1,1'-[Dithiobis(methylene)]biscyclopropaneacetic Acid
Catalogue No.	VQ-026771
CAS Number	162515-67-5
IUPAC name	2-[1-[[[1-(carboxymethyl)cyclopropyl]methyldisulfanyl]methyl]cyclopropyl]acetic acid
Molecular formula	C₁₂H₁₈O₄S₂
Molecular weight	290.4 g/mol
Exact mass	290.0647
Grade	Reference Standard
HSN code	38229090
InChIKey	CUVZSQALKWWFBI-UHFFFAOYSA-N
SMILES	C1CC1(CC(=O)O)CSSCC2(CC2)CC(=O)O
PubChem CID	9835654

Physical properties
Physical form	Solid
LogP (XLogP3)	1.1
H-bond donors / acceptors	2 / 6
TPSA	125 Å²
Synonyms	(1-(1-Carboxymethyl-cyclopropylmethyldisulfanylmethyl)-cyclopropyl)-essigsaure, [1-(1-Carboxymethyl-cyclopropylmethyldisulfanylmethyl)-cyclopropyl]-essigsaure, Cyclopropaneacetic acid, 1,1'-[dithiobis(methylene)]bis-, 2,2'-((Disulfanediylbis(methylene))bis(cyclopropane-1,1-diyl))diacetic acid, 2-{1-[({[1-(carboxymethyl)cyclopropyl]methyl}disulfanyl)methyl]cyclopropyl}acetic acid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1,1'-[Dithiobis(methylene)]biscyclopropaneacetic Acid?

The CAS Registry Number of 1,1'-[Dithiobis(methylene)]biscyclopropaneacetic Acid is 162515-67-5. It is also known as (1-(1-Carboxymethyl-cyclopropylmethyldisulfanylmethyl)-cyclopropyl)-essigsaure, [1-(1-Carboxymethyl-cyclopropylmethyldisulfanylmethyl)-cyclopropyl]-essigsaure, Cyclopropaneacetic acid, 1,1'-[dithiobis(methylene)]bis-.

What is the molecular formula and molecular weight of 1,1'-[Dithiobis(methylene)]biscyclopropaneacetic Acid?

1,1'-[Dithiobis(methylene)]biscyclopropaneacetic Acid has the molecular formula C12H18O4S2 and a molecular weight of 290.4 g/mol. Its IUPAC name is 2-[1-[[[1-(carboxymethyl)cyclopropyl]methyldisulfanyl]methyl]cyclopropyl]acetic acid.

What is 1,1'-[Dithiobis(methylene)]biscyclopropaneacetic Acid used for?

1,1'-[Dithiobis(methylene)]biscyclopropaneacetic Acid is supplied as a characterised reference material related to Montelukast. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1,1'-[Dithiobis(methylene)]biscyclopropaneacetic Acid can I order?

We supply 1,1'-[Dithiobis(methylene)]biscyclopropaneacetic Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1,1'-[Dithiobis(methylene)]biscyclopropaneacetic Acid?

Yes. Every lot of 1,1'-[Dithiobis(methylene)]biscyclopropaneacetic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1,1'-[Dithiobis(methylene)]biscyclopropaneacetic Acid be shipped internationally?

Yes. 1,1'-[Dithiobis(methylene)]biscyclopropaneacetic Acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.