4'-O-Benzyloxy Ezetimibe

Name: 4'-O-Benzyloxy Ezetimibe
Brand: Vaqora Chemicals
SKU: VQ-025691

About 4'-O-Benzyloxy Ezetimibe

Listed under CAS 163222-32-0, 4'-O-Benzyloxy Ezetimibe is a metabolite or degradation product of Ezetimibe available from Vaqora Chemicals. With the molecular formula C31H27F2NO3, it has a molar mass of 499.5 g/mol. The IUPAC name is (3R,4S)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-phenylmethoxyphenyl)azetidin-2-one. It is also known as Ezetimibe Intermediate-L or Hydroxy Benzylated Ezetimibe.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Analytical teams use this compound to identify metabolites and degradants of Ezetimibe, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 4'-O-Benzyloxy Ezetimibe is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling
Fine chemical synthesis

Industries

Related to Ezetimibe

View every impurity, metabolite and intermediate we list for Ezetimibe.

Ezetimibe impurities

Specifications & identifiers

Chemical identifiers
Product name	4'-O-Benzyloxy Ezetimibe
Catalogue No.	VQ-025691
CAS Number	163222-32-0
IUPAC name	(3R,4S)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-phenylmethoxyphenyl)azetidin-2-one
Molecular formula	C₃₁H₂₇F₂NO₃
Molecular weight	499.5 g/mol
Exact mass	499.1959
Grade	Reference Standard
HSN code	38229090
InChIKey	KEYVFYMGVLFXQK-DYIKCSJPSA-N
SMILES	C1=CC=C(C=C1)COC2=CC=C(C=C2)[C@@H]3[C@H](C(=O)N3C4=CC=C(C=C4)F)CC[C@@H](C5=CC=C(C=C5)F)O
PubChem CID	10577302

Physical properties
Physical form	Solid
LogP (XLogP3)	5.8
H-bond donors / acceptors	1 / 5
TPSA	49.8 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4'-O-Benzyloxy Ezetimibe?

The CAS Registry Number of 4'-O-Benzyloxy Ezetimibe is 163222-32-0. It is also known as Ezetimibe Intermediate-L, Hydroxy Benzylated Ezetimibe, 4'-O-Benzyl Ezetimibe.

What is the molecular formula and molecular weight of 4'-O-Benzyloxy Ezetimibe?

4'-O-Benzyloxy Ezetimibe has the molecular formula C31H27F2NO3 and a molecular weight of 499.5 g/mol. Its IUPAC name is (3R,4S)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-phenylmethoxyphenyl)azetidin-2-one.

What is 4'-O-Benzyloxy Ezetimibe used for?

4'-O-Benzyloxy Ezetimibe is supplied as a characterised reference material related to Ezetimibe. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4'-O-Benzyloxy Ezetimibe can I order?

We supply 4'-O-Benzyloxy Ezetimibe in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4'-O-Benzyloxy Ezetimibe?

Yes. Every lot of 4'-O-Benzyloxy Ezetimibe is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4'-O-Benzyloxy Ezetimibe be shipped internationally?

Yes. We export 4'-O-Benzyloxy Ezetimibe worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.