4-Methyl-4-(methylnitrosoamino)-2-pentanone

Name: 4-Methyl-4-(methylnitrosoamino)-2-pentanone
Brand: Vaqora Chemicals
SKU: VQ-034535

About 4-Methyl-4-(methylnitrosoamino)-2-pentanone

Vaqora Chemicals supplies 4-Methyl-4-(methylnitrosoamino)-2-pentanone, a nitrosamine impurity of Valsartan registered under CAS number 16339-21-2. The compound has the formula C7H14N2O2, corresponding to a molecular weight of 158.2 g/mol. The IUPAC name is N-methyl-N-(2-methyl-4-oxopentan-2-yl)nitrous amide. Alternative names: 4-Methyl-4-(N-nitrosomethylamino)-2-pentanone and 4-methyl-4-[methyl(nitroso)amino]pentan-2-one.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

It is used as a reference standard for trace-level detection and quantitation of nitrosamine impurities by LC-MS/MS or GC-MS, supporting nitrosamine risk assessments for Valsartan, method validation (AMV) and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer 4-Methyl-4-(methylnitrosoamino)-2-pentanone in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Valsartan

View every impurity, metabolite and intermediate we list for Valsartan.

Valsartan impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Methyl-4-(methylnitrosoamino)-2-pentanone
Catalogue No.	VQ-034535
CAS Number	16339-21-2
IUPAC name	N-methyl-N-(2-methyl-4-oxopentan-2-yl)nitrous amide
Molecular formula	C₇H₁₄N₂O₂
Molecular weight	158.2 g/mol
Exact mass	158.1055
Grade	Reference Standard
HSN code	38229090
InChIKey	BUFWFGAUZTUMMV-UHFFFAOYSA-N
SMILES	CC(=O)CC(C)(C)N(C)N=O
PubChem CID	85370

Physical properties
Physical form	Solid
LogP (XLogP3)	0.5
H-bond donors / acceptors	0 / 4
TPSA	49.7 Å²
Synonyms	2-Pentanone, 4-methyl-4-(N-nitrosomethylamino)-, 4-Methyl-4-(N-nitrosomethylamino)-2-pentanone, 4-methyl-4-[methyl(nitroso)amino]pentan-2-one, 2-Methylnitrosamino-2-methylpentanon(4), Methyl-1,1-dimethylbutanon(3)-nitrosamin

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Methyl-4-(methylnitrosoamino)-2-pentanone?

The CAS Registry Number of 4-Methyl-4-(methylnitrosoamino)-2-pentanone is 16339-21-2. It is also known as 2-Pentanone, 4-methyl-4-(N-nitrosomethylamino)-, 4-Methyl-4-(N-nitrosomethylamino)-2-pentanone, 4-methyl-4-[methyl(nitroso)amino]pentan-2-one.

What is the molecular formula and molecular weight of 4-Methyl-4-(methylnitrosoamino)-2-pentanone?

4-Methyl-4-(methylnitrosoamino)-2-pentanone has the molecular formula C7H14N2O2 and a molecular weight of 158.2 g/mol. Its IUPAC name is N-methyl-N-(2-methyl-4-oxopentan-2-yl)nitrous amide.

What is 4-Methyl-4-(methylnitrosoamino)-2-pentanone used for?

4-Methyl-4-(methylnitrosoamino)-2-pentanone is supplied as a characterised reference material related to Valsartan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Methyl-4-(methylnitrosoamino)-2-pentanone can I order?

We supply 4-Methyl-4-(methylnitrosoamino)-2-pentanone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Methyl-4-(methylnitrosoamino)-2-pentanone?

Yes. Every lot of 4-Methyl-4-(methylnitrosoamino)-2-pentanone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Methyl-4-(methylnitrosoamino)-2-pentanone be shipped internationally?

Yes. We export 4-Methyl-4-(methylnitrosoamino)-2-pentanone worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.