Glibenclamide - Impurity A | CAS 16673-34-0

Name: Glibenclamide - Impurity A
Brand: Vaqora Chemicals
SKU: VQ-022757

About Glibenclamide - Impurity A

Listed under CAS 16673-34-0, Glibenclamide - Impurity A is an impurity of Glyburide available from Vaqora Chemicals. The compound has the formula C16H17ClN2O4S, corresponding to a molecular weight of 368.8 g/mol. Its systematic (IUPAC) name is 5-chloro-2-methoxy-N-[2-(4-sulfamoylphenyl)ethyl]benzamide. Common synonyms include Glibenclamide EP Impurity A and Glyburide USP Related Compound A.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

This Glyburide impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Glibenclamide - Impurity A in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Glyburide

View every impurity, metabolite and intermediate we list for Glyburide.

Glyburide impurities

Specifications & identifiers

Chemical identifiers
Product name	Glibenclamide - Impurity A
Catalogue No.	VQ-022757
CAS Number	16673-34-0
IUPAC name	5-chloro-2-methoxy-N-[2-(4-sulfamoylphenyl)ethyl]benzamide
Molecular formula	C₁₆H₁₇ClN₂O₄S
Molecular weight	368.8 g/mol
Exact mass	368.0598
Grade	Reference Standard
HSN code	38229090
InChIKey	KVWWTCSJLGHLRM-UHFFFAOYSA-N
SMILES	COC1=C(C=C(C=C1)Cl)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)N
PubChem CID	85542

Physical properties
Physical form	Solid
LogP (XLogP3)	2.4
H-bond donors / acceptors	2 / 5
TPSA	107 Å²
Synonyms	Glibenclamide EP Impurity A, Glyburide USP Related Compound A, Glyburide Impurity A, 5-chloro-2-methoxy-N-(2-(4-sulfamoylphenyl)ethyl)benzamide, 5-Chloro-2-methoxy-N-(4-sulfamoylphenethyl)benzamide, NLRP3 Inflammasome Inhibitor I, 4-[2-(5-Chloro-2-methoxybenzamido)ethyl]benzene Sulfonamide, 4-[2-(5-Chloro-2-methoxybenzamido)ethyl]phenylsulfonamide, N-(2-(4-sulfamoyl)phenyl)ethyl-5-chloro-2-methoxybenzamide, 4-[2-(5-Chloro-2-methoxybenzamido) ethyl] benzenesulfonamide, Benzamide, N-(2-(4-(aminosulfonyl)phenyl)ethyl)-5-chloro-2-methoxy-

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Glibenclamide - Impurity A?

The CAS Registry Number of Glibenclamide - Impurity A is 16673-34-0. It is also known as Glibenclamide EP Impurity A, Glyburide USP Related Compound A, Glyburide Impurity A.

What is the molecular formula and molecular weight of Glibenclamide - Impurity A?

Glibenclamide - Impurity A has the molecular formula C16H17ClN2O4S and a molecular weight of 368.8 g/mol. Its IUPAC name is 5-chloro-2-methoxy-N-[2-(4-sulfamoylphenyl)ethyl]benzamide.

What is Glibenclamide - Impurity A used for?

Glibenclamide - Impurity A is supplied as a characterised reference material related to Glyburide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Glibenclamide - Impurity A can I order?

We supply Glibenclamide - Impurity A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Glibenclamide - Impurity A?

Yes. Every lot of Glibenclamide - Impurity A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Glibenclamide - Impurity A be shipped internationally?

Yes. Glibenclamide - Impurity A is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.