(R)-Zanubrutinib

About (R)-Zanubrutinib

(R)-Zanubrutinib is a high-purity reference standard of Zanubrutinib carrying the CAS registry number 1691249-44-1. The compound has the formula C27H29N5O3, corresponding to a molecular weight of 471.5 g/mol. It is also known as Zanubrutinib R-isomer or (S)-Zanubrutinib.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Laboratories use this Zanubrutinib standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Zanubrutinib

View every impurity, metabolite and intermediate we list for Zanubrutinib.

Zanubrutinib impurities

Specifications & identifiers

Chemical identifiers
Product name	(R)-Zanubrutinib
Catalogue No.	VQ-021364
CAS Number	1691249-44-1
IUPAC name	(7R)-2-(4-phenoxyphenyl)-7-(1-prop-2-enoylpiperidin-4-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide
Molecular formula	C₂₇H₂₉N₅O₃
Molecular weight	471.5 g/mol
Exact mass	471.227
Grade	Reference Standard
HSN code	38229090
InChIKey	RNOAOAWBMHREKO-JOCHJYFZSA-N
SMILES	C=CC(=O)N1CCC(CC1)[C@H]2CCNC3=C(C(=NN23)C4=CC=C(C=C4)OC5=CC=CC=C5)C(=O)N
PubChem CID	137071299

Physical properties
Physical form	Solid
LogP (XLogP3)	3.5
H-bond donors / acceptors	2 / 5
TPSA	102 Å²
Synonyms	Zanubrutinib R-isomer, (S)-Zanubrutinib, Zanubrutinib, (R)-, EX-A3705, (R)-BGB-3111, US20250340560, Compound 27a, US9447106, 27a (peak 1)

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (R)-Zanubrutinib?

The CAS Registry Number of (R)-Zanubrutinib is 1691249-44-1. It is also known as Zanubrutinib R-isomer, (S)-Zanubrutinib, Zanubrutinib, (R)-.

What is the molecular formula and molecular weight of (R)-Zanubrutinib?

(R)-Zanubrutinib has the molecular formula C27H29N5O3 and a molecular weight of 471.5 g/mol. Its IUPAC name is (7R)-2-(4-phenoxyphenyl)-7-(1-prop-2-enoylpiperidin-4-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide.

What is (R)-Zanubrutinib used for?

(R)-Zanubrutinib is supplied as a characterised reference material related to Zanubrutinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (R)-Zanubrutinib can I order?

We supply (R)-Zanubrutinib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (R)-Zanubrutinib?

Yes. Every lot of (R)-Zanubrutinib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (R)-Zanubrutinib be shipped internationally?

Yes. We export (R)-Zanubrutinib worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.