Hydroxy Celecoxib

About Hydroxy Celecoxib

Hydroxy Celecoxib is a metabolite or degradation product of Celecoxib carrying the CAS registry number 170571-00-3. With the molecular formula C17H14F3N3O3S, it has a molar mass of 397.4 g/mol. Its systematic (IUPAC) name is 4-[5-[4-(hydroxymethyl)phenyl]-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide. It is also known as Celecoxib Hydroxymethyl Analog or Hydroxy Methyl Celecoxib.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 1 hazard statement. Review the Safety Data Sheet before use.

Analytical teams use this compound to identify metabolites and degradants of Celecoxib, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Hydroxy Celecoxib in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Celecoxib

View every impurity, metabolite and intermediate we list for Celecoxib.

Celecoxib impurities

Specifications & identifiers

Chemical identifiers
Product name	Hydroxy Celecoxib
Catalogue No.	VQ-024087
CAS Number	170571-00-3
IUPAC name	4-[5-[4-(hydroxymethyl)phenyl]-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide
Molecular formula	C₁₇H₁₄F₃N₃O₃S
Molecular weight	397.4 g/mol
Exact mass	397.0708
Grade	Reference Standard
HSN code	38229090
InChIKey	ICRSYPPLGADZKA-UHFFFAOYSA-N
SMILES	C1=CC(=CC=C1CO)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F
PubChem CID	9908776

Physical properties
Physical form	Solid
LogP (XLogP3)	2.2
H-bond donors / acceptors	2 / 8
TPSA	107 Å²
Synonyms	Celecoxib Hydroxymethyl Analog, Hydroxy Methyl Celecoxib, Hydroxymethyl Celecoxib, 4'-Hydroxycelecoxib, Celecoxib metabolite M3, 4-(5-(4-Hydroxymethylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide, Benzenesulfonamide, 4-(5-(4-(hydroxymethyl)phenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)-, 4-[5-(4-Hydroxymethylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide, BenzenesulfonaMide, 4-[5-[4-(hydroxyMethyl)phenyl]-3-(trifluoroMethyl)-1H-pyrazol-1-yl]-, 4-(5-(4-(Hydroxymethyl)phenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide, Methylhydroxy-Celecoxib, 4-[5-[4-(Hydroxymethyl)phenyl]-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Hydroxy Celecoxib?

The CAS Registry Number of Hydroxy Celecoxib is 170571-00-3. It is also known as Celecoxib Hydroxymethyl Analog, Hydroxy Methyl Celecoxib, Hydroxymethyl Celecoxib.

What is the molecular formula and molecular weight of Hydroxy Celecoxib?

Hydroxy Celecoxib has the molecular formula C17H14F3N3O3S and a molecular weight of 397.4 g/mol. Its IUPAC name is 4-[5-[4-(hydroxymethyl)phenyl]-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide.

What is Hydroxy Celecoxib used for?

Hydroxy Celecoxib is supplied as a characterised reference material related to Celecoxib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Hydroxy Celecoxib can I order?

We supply Hydroxy Celecoxib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Hydroxy Celecoxib?

Yes. Every lot of Hydroxy Celecoxib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Hydroxy Celecoxib be shipped internationally?

Yes. Hydroxy Celecoxib is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.