N-Demethylazithromycin

Name: N-Demethylazithromycin
Brand: Vaqora Chemicals
SKU: VQ-020878

About N-Demethylazithromycin

N-Demethylazithromycin (CAS 172617-84-4) is a metabolite or degradation product of Azithromycin offered by Vaqora Chemicals. The compound has the formula C37H70N2O12, corresponding to a molecular weight of 735.0 g/mol. It is also known as N'-(Desmethyl)azithromycin or 3'-N-Demethylazithromycin.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Azithromycin, as well as in QC testing and ANDA/DMF documentation. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer N-Demethylazithromycin in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Azithromycin

View every impurity, metabolite and intermediate we list for Azithromycin.

Azithromycin impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Demethylazithromycin
Catalogue No.	VQ-020878
CAS Number	172617-84-4
IUPAC name	(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-11-[(2S,3R,4S,6R)-3-hydroxy-6-methyl-4-(methylamino)oxan-2-yl]oxy-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one
Molecular formula	C₃₇H₇₀N₂O₁₂
Molecular weight	735 g/mol
Exact mass	734.4929
Grade	Reference Standard
HSN code	38229090
InChIKey	FZYUKBLYECHAGN-HOQMJRDDSA-N
SMILES	CC[C@@H]1[C@@]([C@@H]([C@H](N(C[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)NC)O)(C)O)C)C)C)O)(C)O
PubChem CID	9987533

Physical properties
Physical form	Solid
LogP (XLogP3)	3.6
H-bond donors / acceptors	6 / 14
TPSA	189 Å²
Synonyms	N'-(Desmethyl)azithromycin, 3'-N-Demethylazithromycin, N'-Desmethyl Azithromycin, 3'-N-Desmethylazithromycin, N-desmethyl azithromycin

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Demethylazithromycin?

The CAS Registry Number of N-Demethylazithromycin is 172617-84-4. It is also known as N'-(Desmethyl)azithromycin, 3'-N-Demethylazithromycin, N'-Desmethyl Azithromycin.

What is the molecular formula and molecular weight of N-Demethylazithromycin?

N-Demethylazithromycin has the molecular formula C37H70N2O12 and a molecular weight of 735 g/mol.

What is N-Demethylazithromycin used for?

N-Demethylazithromycin is supplied as a characterised reference material related to Azithromycin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Demethylazithromycin can I order?

We supply N-Demethylazithromycin in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Demethylazithromycin?

Yes. Every lot of N-Demethylazithromycin is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Demethylazithromycin be shipped internationally?

Yes. We export N-Demethylazithromycin worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.