6alpha-Chloro Dexamethasone

About 6alpha-Chloro Dexamethasone

6alpha-Chloro Dexamethasone is an impurity of Flumethasone carrying the CAS registry number 1744-64-5. With the molecular formula C22H28ClFO5, it has a molar mass of 426.9 g/mol.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Flumethasone, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Flumethasone

View every impurity, metabolite and intermediate we list for Flumethasone.

Flumethasone impurities

Specifications & identifiers

Chemical identifiers
Product name	6alpha-Chloro Dexamethasone
Catalogue No.	VQ-030787
CAS Number	1744-64-5
IUPAC name	(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6-chloro-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
Molecular formula	C₂₂H₂₈ClFO₅
Molecular weight	426.9 g/mol
Exact mass	426.1609
Grade	Reference Standard
HSN code	38229090
InChIKey	CDGJSUBGFOVZMH-GQKYHHCASA-N
SMILES	C[C@@H]1C[C@H]2[C@@H]3C[C@@H](C4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CO)O)C)O)F)C)Cl
PubChem CID	69421477

Physical properties
Physical form	Solid
LogP (XLogP3)	2.2
H-bond donors / acceptors	3 / 6
TPSA	94.8 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P321, P330, P332 + P317, P337 + P317, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 6alpha-Chloro Dexamethasone?

The CAS Registry Number of 6alpha-Chloro Dexamethasone is 1744-64-5. It is also known as 6alpha-Chloro-9-fluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione.

What is the molecular formula and molecular weight of 6alpha-Chloro Dexamethasone?

6alpha-Chloro Dexamethasone has the molecular formula C22H28ClFO5 and a molecular weight of 426.9 g/mol.

What is 6alpha-Chloro Dexamethasone used for?

6alpha-Chloro Dexamethasone is supplied as a characterised reference material related to Flumethasone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 6alpha-Chloro Dexamethasone can I order?

We supply 6alpha-Chloro Dexamethasone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 6alpha-Chloro Dexamethasone?

Yes. Every lot of 6alpha-Chloro Dexamethasone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 6alpha-Chloro Dexamethasone be shipped internationally?

Yes. 6alpha-Chloro Dexamethasone is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.