2-Hydroxymethyl Olanzapine

About 2-Hydroxymethyl Olanzapine

2-Hydroxymethyl Olanzapine is a metabolite or degradation product of Olanzapine carrying the CAS registry number 174756-45-7. The compound has the formula C17H20N4OS, corresponding to a molecular weight of 328.4 g/mol. The IUPAC name is [4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepin-2-yl]methanol.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Analytical teams use this compound to identify metabolites and degradants of Olanzapine, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling
Fine chemical synthesis

Industries

Related to Olanzapine

View every impurity, metabolite and intermediate we list for Olanzapine.

Olanzapine impurities

Specifications & identifiers

Chemical identifiers
Product name	2-Hydroxymethyl Olanzapine
Catalogue No.	VQ-026986
CAS Number	174756-45-7
IUPAC name	[4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepin-2-yl]methanol
Molecular formula	C₁₇H₂₀N₄OS
Molecular weight	328.4 g/mol
Exact mass	328.1358
Grade	Reference Standard
HSN code	38229090
InChIKey	FPDIERBPQFAFSI-UHFFFAOYSA-N
SMILES	CN1CCN(CC1)C2=NC3=CC=CC=C3NC4=C2C=C(S4)CO
PubChem CID	135515431

Physical properties
Physical form	Solid
LogP (XLogP3)	1.6
H-bond donors / acceptors	2 / 5
TPSA	79.3 Å²
Synonyms	10H-Thieno(2,3-b)(1,5)benzodiazepine-2-methanol, 4-(4-methyl-1-piperazinyl)-, 4-(4-Methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine-2-methanol, 4-(4-Methyl-1-piperazinyl)-10H-thieno(2,3-b)(1,5)benzodiazepine-2-methanol, 10H-Thieno[2,3-b][1,5]benzodiazepine-2-methanol, 4-(4-methyl-1-piperazinyl)-, (4-(4-Methylpiperazin-1-yl)-10H-benzo[b]thieno[2,3-e][1,4]diazepin-2-yl)methanol, [10-(4-Methyl-piperazin-1-yl)-4H-3-thia-4,9-diaza-benzo[f]azulen-2-yl]-methanol, [4-(4-Methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepin-2-yl]methanol, [4-(4-Methylpiperazin-1-yl)-5H-thieno[2,3-b][1,5]benzodiazepin-2-yl]methanol

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Hydroxymethyl Olanzapine?

The CAS Registry Number of 2-Hydroxymethyl Olanzapine is 174756-45-7. It is also known as 10H-Thieno(2,3-b)(1,5)benzodiazepine-2-methanol, 4-(4-methyl-1-piperazinyl)-, 4-(4-Methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine-2-methanol, 4-(4-Methyl-1-piperazinyl)-10H-thieno(2,3-b)(1,5)benzodiazepine-2-methanol.

What is the molecular formula and molecular weight of 2-Hydroxymethyl Olanzapine?

2-Hydroxymethyl Olanzapine has the molecular formula C17H20N4OS and a molecular weight of 328.4 g/mol. Its IUPAC name is [4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepin-2-yl]methanol.

What is 2-Hydroxymethyl Olanzapine used for?

2-Hydroxymethyl Olanzapine is supplied as a characterised reference material related to Olanzapine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Hydroxymethyl Olanzapine can I order?

We supply 2-Hydroxymethyl Olanzapine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Hydroxymethyl Olanzapine?

Yes. Every lot of 2-Hydroxymethyl Olanzapine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Hydroxymethyl Olanzapine be shipped internationally?

Yes. We export 2-Hydroxymethyl Olanzapine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.