N-4-Methoxybenzyl efavirenz

About N-4-Methoxybenzyl efavirenz

N-4-Methoxybenzyl efavirenz is an impurity of Efavirenz carrying the CAS registry number 174819-21-7. Formula C22H17ClF3NO3, molecular weight 435.8 g/mol. The IUPAC name is (4S)-6-chloro-4-(2-cyclopropylethynyl)-1-[(4-methoxyphenyl)methyl]-4-(trifluoromethyl)-3,1-benzoxazin-2-one. Alternative names: N-Benzyl Efavirenz and N-p-methoxypheny Efavirenz.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Efavirenz to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Efavirenz

View every impurity, metabolite and intermediate we list for Efavirenz.

Efavirenz impurities

Specifications & identifiers

Chemical identifiers
Product name	N-4-Methoxybenzyl efavirenz
Catalogue No.	VQ-021214
CAS Number	174819-21-7
IUPAC name	(4S)-6-chloro-4-(2-cyclopropylethynyl)-1-[(4-methoxyphenyl)methyl]-4-(trifluoromethyl)-3,1-benzoxazin-2-one
Molecular formula	C₂₂H₁₇ClF₃NO₃
Molecular weight	435.8 g/mol
Exact mass	435.0849
Grade	Reference Standard
HSN code	38229090
InChIKey	BKYROQXKHLSLOS-NRFANRHFSA-N
SMILES	COC1=CC=C(C=C1)CN2C3=C(C=C(C=C3)Cl)[C@@](OC2=O)(C#CC4CC4)C(F)(F)F
PubChem CID	11112909

Physical properties
Physical form	Solid
LogP (XLogP3)	5.7
H-bond donors / acceptors	0 / 6
TPSA	38.8 Å²
Synonyms	N-Benzyl Efavirenz, N-p-methoxypheny Efavirenz, SE-563, SE 563, N-Benzylefavirenzi

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-4-Methoxybenzyl efavirenz?

The CAS Registry Number of N-4-Methoxybenzyl efavirenz is 174819-21-7. It is also known as N-Benzyl Efavirenz, N-p-methoxypheny Efavirenz, SE-563.

What is the molecular formula and molecular weight of N-4-Methoxybenzyl efavirenz?

N-4-Methoxybenzyl efavirenz has the molecular formula C22H17ClF3NO3 and a molecular weight of 435.8 g/mol. Its IUPAC name is (4S)-6-chloro-4-(2-cyclopropylethynyl)-1-[(4-methoxyphenyl)methyl]-4-(trifluoromethyl)-3,1-benzoxazin-2-one.

What is N-4-Methoxybenzyl efavirenz used for?

N-4-Methoxybenzyl efavirenz is supplied as a characterised reference material related to Efavirenz. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-4-Methoxybenzyl efavirenz can I order?

We supply N-4-Methoxybenzyl efavirenz in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-4-Methoxybenzyl efavirenz?

Yes. Every lot of N-4-Methoxybenzyl efavirenz is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-4-Methoxybenzyl efavirenz be shipped internationally?

Yes. We export N-4-Methoxybenzyl efavirenz worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.