Cis-Terbinafine Hydrochloride

About Cis-Terbinafine Hydrochloride

Cis-Terbinafine Hydrochloride is an impurity of Terbinafine carrying the CAS registry number 176168-78-8. The compound has the formula C21H26ClN, corresponding to a molecular weight of 327.9 g/mol. Alternative names: Terbinafine hydrochloride, (Z)- and (Z)-terbinafine hydrochloride.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Terbinafine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Terbinafine

View every impurity, metabolite and intermediate we list for Terbinafine.

Terbinafine impurities

Specifications & identifiers

Chemical identifiers
Product name	Cis-Terbinafine Hydrochloride
Catalogue No.	VQ-042438
CAS Number	176168-78-8
IUPAC name	(Z)-N,6,6-trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine;hydrochloride
Molecular formula	C₂₁H₂₆ClN
Molecular weight	327.9 g/mol
Exact mass	327.1754
Grade	Reference Standard
HSN code	38229090
InChIKey	BWMISRWJRUSYEX-UYTGOYFPSA-N
SMILES	CC(C)(C)C#C/C=C\CN(C)CC1=CC=CC2=CC=CC=C21.Cl
PubChem CID	71752365

Physical properties
Physical form	Solid
H-bond donors / acceptors	1 / 1
TPSA	3.2 Å²
Synonyms	Terbinafine hydrochloride, (Z)-, (2Z)-N,6,6-Trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine hydrochloride, (Z)-N,6,6-Trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine hydrochloride, (Z)-terbinafine hydrochloride, N-[(2Z)-6,6-Dimethyl-2-hepten-4-yn-1-yl]-N-methyl-1-naphthalenemethanamine Hydrochloride, (Z)-N,6,6-Trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-aminehydrochloride

Safety & hazard information (GHS)

Harmful / irritant

Environmental hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P264, P270, P273, P301 + P317, P330, P391, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Cis-Terbinafine Hydrochloride?

The CAS Registry Number of Cis-Terbinafine Hydrochloride is 176168-78-8. It is also known as Terbinafine hydrochloride, (Z)-, (2Z)-N,6,6-Trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine hydrochloride, (Z)-N,6,6-Trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine hydrochloride.

What is the molecular formula and molecular weight of Cis-Terbinafine Hydrochloride?

Cis-Terbinafine Hydrochloride has the molecular formula C21H26ClN and a molecular weight of 327.9 g/mol.

What is Cis-Terbinafine Hydrochloride used for?

Cis-Terbinafine Hydrochloride is supplied as a characterised reference material related to Terbinafine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Cis-Terbinafine Hydrochloride can I order?

We supply Cis-Terbinafine Hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Cis-Terbinafine Hydrochloride?

Yes. Every lot of Cis-Terbinafine Hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Cis-Terbinafine Hydrochloride be shipped internationally?

Yes. Cis-Terbinafine Hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.