N-Desmethyl Dofetilide

Name: N-Desmethyl Dofetilide
Brand: Vaqora Chemicals
SKU: VQ-025357

About N-Desmethyl Dofetilide

N-Desmethyl Dofetilide (CAS 176447-94-2) is a metabolite or degradation product of Dofetilide offered by Vaqora Chemicals. With the molecular formula C18H25N3O5S2, it has a molar mass of 427.5 g/mol. Systematically, it is named N-[4-[2-[2-[4-(methanesulfonamido)phenoxy]ethylamino]ethyl]phenyl]methanesulfonamide. It is also known as N-DesMethyldofetilifide or EX-A598.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Analytical teams use this compound to identify metabolites and degradants of Dofetilide, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, N-Desmethyl Dofetilide is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Dofetilide

View every impurity, metabolite and intermediate we list for Dofetilide.

Dofetilide impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Desmethyl Dofetilide
Catalogue No.	VQ-025357
CAS Number	176447-94-2
IUPAC name	N-[4-[2-[2-[4-(methanesulfonamido)phenoxy]ethylamino]ethyl]phenyl]methanesulfonamide
Molecular formula	C₁₈H₂₅N₃O₅S₂
Molecular weight	427.5 g/mol
Exact mass	427.1236
Grade	Reference Standard
HSN code	38229090
InChIKey	JITIJIUDNAYXKK-UHFFFAOYSA-N
SMILES	CS(=O)(=O)NC1=CC=C(C=C1)CCNCCOC2=CC=C(C=C2)NS(=O)(=O)C
PubChem CID	10455225

Physical properties
Physical form	Solid
LogP (XLogP3)	1.4
H-bond donors / acceptors	3 / 8
TPSA	130 Å²
Synonyms	N-(4-(2-(2-(4-(Methanesulfonamido)phenoxy)ethyl)amino)phenyl)methanesulfonamide, N-[4-(2-(2-[4-(methanesulfonamido)phenoxy]ethyl)amino)phenyl]methanesulfonamide, N-(4-(2-((4-(Methylsulfonamido)phenethyl)amino)ethoxy)phenyl)methanesulfonamide, N-DesMethyldofetilifide, N-[4-(2-{[2-(4-methanesulfonamidophenoxy)ethyl]amino}ethyl)phenyl]methanesulfonamide, N-[4-[2-[[2-[4-[(Methylsulfonyl)amino]phenoxy]ethyl]amino]ethyl]phenyl]methanesulfonamide, EX-A598

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H360May damage fertility or the unborn child

Precautionary statements: P203, P264, P270, P280, P301 + P317, P318, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Desmethyl Dofetilide?

The CAS Registry Number of N-Desmethyl Dofetilide is 176447-94-2. It is also known as N-(4-(2-(2-(4-(Methanesulfonamido)phenoxy)ethyl)amino)phenyl)methanesulfonamide, N-[4-(2-(2-[4-(methanesulfonamido)phenoxy]ethyl)amino)phenyl]methanesulfonamide, N-(4-(2-((4-(Methylsulfonamido)phenethyl)amino)ethoxy)phenyl)methanesulfonamide.

What is the molecular formula and molecular weight of N-Desmethyl Dofetilide?

N-Desmethyl Dofetilide has the molecular formula C18H25N3O5S2 and a molecular weight of 427.5 g/mol. Its IUPAC name is N-[4-[2-[2-[4-(methanesulfonamido)phenoxy]ethylamino]ethyl]phenyl]methanesulfonamide.

What is N-Desmethyl Dofetilide used for?

N-Desmethyl Dofetilide is supplied as a characterised reference material related to Dofetilide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Desmethyl Dofetilide can I order?

We supply N-Desmethyl Dofetilide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Desmethyl Dofetilide?

Yes. Every lot of N-Desmethyl Dofetilide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Desmethyl Dofetilide be shipped internationally?

Yes. N-Desmethyl Dofetilide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.