(R,S)-Norcotinine

Name: (R,S)-Norcotinine
Brand: Vaqora Chemicals
SKU: VQ-049226

About (R,S)-Norcotinine

Listed under CAS 17708-87-1, (R,S)-Norcotinine is a process intermediate or related compound of Nicotine Hemisulfate available from Vaqora Chemicals. Formula C9H10N2O, molecular weight 162.19 g/mol. Its systematic (IUPAC) name is 5-pyridin-3-ylpyrrolidin-2-one. Common synonyms include norcotinine and 5-(3-pyridinyl)-2-pyrrolidinone.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Process chemists and analysts use it when developing synthetic routes to Nicotine Hemisulfate, tracking process-related impurities and validating analytical methods. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer (R,S)-Norcotinine in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Nicotine Hemisulfate

View every impurity, metabolite and intermediate we list for Nicotine Hemisulfate.

Nicotine Hemisulfate impurities

Specifications & identifiers

Chemical identifiers
Product name	(R,S)-Norcotinine
Catalogue No.	VQ-049226
CAS Number	17708-87-1
IUPAC name	5-pyridin-3-ylpyrrolidin-2-one
Molecular formula	C₉H₁₀N₂O
Molecular weight	162.19 g/mol
Exact mass	162.0793
HSN code	2933
InChIKey	FXFANIORDKRCCA-UHFFFAOYSA-N
SMILES	C1CC(=O)NC1C2=CN=CC=C2
PubChem CID	413

Physical properties
Physical form	Solid
LogP (XLogP3)	0.1
H-bond donors / acceptors	1 / 2
TPSA	42 Å²
Synonyms	norcotinine, 5-(3-pyridinyl)-2-pyrrolidinone, 5-Pyridin-3-yl-pyrrolidin-2-one, (S)-5-Pyridin-3-yl-pyrrolidin-2-one, 2-Pyrrolidinone, 5-(3-pyridinyl)-, (R)-5-Pyridin-3-yl-pyrrolidin-2-one, (+/-)-Norcotinine, (+/-)-Demethylcotinine, (5RS)-5-(Pyridin-3-yl)pyrrolidin-2-one ((RS)-Norcotinine), rac-Norcotinine

Safety & hazard information (GHS)

Toxic

Signal word: Danger

Hazard statements

H301Toxic if swallowed

Precautionary statements: P264, P270, P301 + P316, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (R,S)-Norcotinine?

The CAS Registry Number of (R,S)-Norcotinine is 17708-87-1. It is also known as norcotinine, 5-(3-pyridinyl)-2-pyrrolidinone, 5-Pyridin-3-yl-pyrrolidin-2-one.

What is the molecular formula and molecular weight of (R,S)-Norcotinine?

(R,S)-Norcotinine has the molecular formula C9H10N2O and a molecular weight of 162.19 g/mol. Its IUPAC name is 5-pyridin-3-ylpyrrolidin-2-one.

What is (R,S)-Norcotinine used for?

(R,S)-Norcotinine is supplied as a characterised reference material related to Nicotine Hemisulfate. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (R,S)-Norcotinine can I order?

We supply (R,S)-Norcotinine, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (R,S)-Norcotinine?

Yes. Every lot of (R,S)-Norcotinine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (R,S)-Norcotinine be shipped internationally?

Yes. (R,S)-Norcotinine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.