Duloxetine N-Desmethyl (S)-Isomer

Name: Duloxetine N-Desmethyl (S)-Isomer
Brand: Vaqora Chemicals
SKU: VQ-048112

About Duloxetine N-Desmethyl (S)-Isomer

Vaqora Chemicals supplies Duloxetine N-Desmethyl (S)-Isomer, a metabolite or degradation product of Duloxetine registered under CAS number 178273-35-3. Its molecular formula is C17H17NOS and its molecular weight is 283.4 g/mol. Systematically, it is named (3S)-3-naphthalen-1-yloxy-3-thiophen-2-ylpropan-1-amine. It is also known as N-Desmethylduloxetine or Duloxetine N-DesMethyl Metabolite.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Analytical teams use this compound to identify metabolites and degradants of Duloxetine, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Duloxetine N-Desmethyl (S)-Isomer in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Duloxetine

View every impurity, metabolite and intermediate we list for Duloxetine.

Duloxetine impurities

Specifications & identifiers

Chemical identifiers
Product name	Duloxetine N-Desmethyl (S)-Isomer
Catalogue No.	VQ-048112
CAS Number	178273-35-3
IUPAC name	(3S)-3-naphthalen-1-yloxy-3-thiophen-2-ylpropan-1-amine
Molecular formula	C₁₇H₁₇NOS
Molecular weight	283.4 g/mol
Exact mass	283.1031
Grade	Reference Standard
HSN code	38229090
InChIKey	ZMXLKLOJDLMZFC-INIZCTEOSA-N
SMILES	C1=CC=C2C(=C1)C=CC=C2O[C@@H](CCN)C3=CC=CS3
PubChem CID	10107888

Physical properties
Physical form	Solid
LogP (XLogP3)	3.8
H-bond donors / acceptors	1 / 3
TPSA	63.5 Å²
Synonyms	N-Desmethylduloxetine, Duloxetine N-DesMethyl Metabolite, (gammaS)-gamma-(1-Naphthalenyloxy)-2-thiophenepropanamine, 2-Thiophenepropanamine, gamma-(1-naphthalenyloxy)-, (S)-, (S)-3-(Naphthalen-1-yloxy)-3-thiophen-2-yl-propylamine

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Duloxetine N-Desmethyl (S)-Isomer?

The CAS Registry Number of Duloxetine N-Desmethyl (S)-Isomer is 178273-35-3. It is also known as N-Desmethylduloxetine, Duloxetine N-DesMethyl Metabolite, (gammaS)-gamma-(1-Naphthalenyloxy)-2-thiophenepropanamine.

What is the molecular formula and molecular weight of Duloxetine N-Desmethyl (S)-Isomer?

Duloxetine N-Desmethyl (S)-Isomer has the molecular formula C17H17NOS and a molecular weight of 283.4 g/mol. Its IUPAC name is (3S)-3-naphthalen-1-yloxy-3-thiophen-2-ylpropan-1-amine.

What is Duloxetine N-Desmethyl (S)-Isomer used for?

Duloxetine N-Desmethyl (S)-Isomer is supplied as a characterised reference material related to Duloxetine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Duloxetine N-Desmethyl (S)-Isomer can I order?

We supply Duloxetine N-Desmethyl (S)-Isomer in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Duloxetine N-Desmethyl (S)-Isomer?

Yes. Every lot of Duloxetine N-Desmethyl (S)-Isomer is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Duloxetine N-Desmethyl (S)-Isomer be shipped internationally?

Yes. We export Duloxetine N-Desmethyl (S)-Isomer worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.