Ambrisentan (R)-Hydroxy Acid Impurity

Name: Ambrisentan (R)-Hydroxy Acid Impurity
Brand: Vaqora Chemicals
SKU: VQ-029087

About Ambrisentan (R)-Hydroxy Acid Impurity

Listed under CAS 178306-49-5, Ambrisentan (R)-Hydroxy Acid Impurity is a metabolite or degradation product of Ambrisentan available from Vaqora Chemicals. Its molecular formula is C16H16O4 and its molecular weight is 272.29 g/mol. Its systematic (IUPAC) name is (2R)-2-hydroxy-3-methoxy-3,3-diphenylpropanoic acid. It is also known as Ambrisentan Hydroxy Acid Impurity (R-Isomer) or Ambrisentan Hydroxy Acid Impurity.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

Analytical teams use this compound to identify metabolites and degradants of Ambrisentan, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Ambrisentan (R)-Hydroxy Acid Impurity in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Ambrisentan

View every impurity, metabolite and intermediate we list for Ambrisentan.

Ambrisentan impurities

Specifications & identifiers

Chemical identifiers
Product name	Ambrisentan (R)-Hydroxy Acid Impurity
Catalogue No.	VQ-029087
CAS Number	178306-49-5
IUPAC name	(2R)-2-hydroxy-3-methoxy-3,3-diphenylpropanoic acid
Molecular formula	C₁₆H₁₆O₄
Molecular weight	272.29 g/mol
Exact mass	272.1049
Grade	Reference Standard
HSN code	38229090
InChIKey	RQJWOLFMWKZKCJ-AWEZNQCLSA-N
SMILES	COC(C1=CC=CC=C1)(C2=CC=CC=C2)[C@H](C(=O)O)O
PubChem CID	51979925

Physical properties
Physical form	Solid
LogP (XLogP3)	2
H-bond donors / acceptors	2 / 4
TPSA	66.8 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ambrisentan (R)-Hydroxy Acid Impurity?

The CAS Registry Number of Ambrisentan (R)-Hydroxy Acid Impurity is 178306-49-5. It is also known as Ambrisentan Hydroxy Acid Impurity (R-Isomer), Ambrisentan Hydroxy Acid Impurity, (R)-2-Hydroxy-3-methoxy-3,3-diphenylpropanoic acid.

What is the molecular formula and molecular weight of Ambrisentan (R)-Hydroxy Acid Impurity?

Ambrisentan (R)-Hydroxy Acid Impurity has the molecular formula C16H16O4 and a molecular weight of 272.29 g/mol. Its IUPAC name is (2R)-2-hydroxy-3-methoxy-3,3-diphenylpropanoic acid.

What is Ambrisentan (R)-Hydroxy Acid Impurity used for?

Ambrisentan (R)-Hydroxy Acid Impurity is supplied as a characterised reference material related to Ambrisentan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ambrisentan (R)-Hydroxy Acid Impurity can I order?

We supply Ambrisentan (R)-Hydroxy Acid Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ambrisentan (R)-Hydroxy Acid Impurity?

Yes. Every lot of Ambrisentan (R)-Hydroxy Acid Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ambrisentan (R)-Hydroxy Acid Impurity be shipped internationally?

Yes. We export Ambrisentan (R)-Hydroxy Acid Impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.