Ritlecitinib

Name: Ritlecitinib
Brand: Vaqora Chemicals
SKU: VQ-007722

About Ritlecitinib

Listed under CAS 1792180-81-4, Ritlecitinib is a high-purity reference standard of Ritlecitinib available from Vaqora Chemicals. Its molecular formula is C15H19N5O and its molecular weight is 285.34 g/mol. Its systematic (IUPAC) name is 1-[(2S,5R)-2-methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)piperidin-1-yl]prop-2-en-1-one. Common synonyms include Litfulo and JAK3 Inhibitor PF-06651600.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 1 hazard statement. Review the Safety Data Sheet before use.

Laboratories use this Ritlecitinib standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Ritlecitinib in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. Stock is available for quick dispatch.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Ritlecitinib

View every impurity, metabolite and intermediate we list for Ritlecitinib.

Ritlecitinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Ritlecitinib
Catalogue No.	VQ-007722
CAS Number	1792180-81-4
Other CAS	2192215-81-7
IUPAC name	1-[(2S,5R)-2-methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)piperidin-1-yl]prop-2-en-1-one
Molecular formula	C₁₅H₁₉N₅O
Molecular weight	285.34 g/mol
Exact mass	285.159
Grade	Reference Standard
HSN code	38229090
InChIKey	CBRJPFGIXUFMTM-WDEREUQCSA-N
SMILES	C[C@H]1CC[C@H](CN1C(=O)C=C)NC2=NC=NC3=C2C=CN3
PubChem CID	118115473

Physical properties
Physical form	Solid
LogP (XLogP3)	2.1
H-bond donors / acceptors	2 / 4
TPSA	73.9 Å²
Synonyms	1-[(2S,5R)-2-Methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-1-piperidinyl]-2-propen-1-one, Litfulo, 1-((2S,5R)-2-methyl-5-(7H-pyrrolo(2,3-d)pyrimidin-4-ylamino)piperidin-1-yl)prop-2-en-1-one, JAK3 Inhibitor PF-06651600, Ritlecitinib (PF-06651600), 1-[(2S,5R)-5-[[7H-Pyrrolo[2,3-d]-4-pyrimidinyl]amino]-2-methyl-1-piperidyl]-2-propen-1-one, PF-06651600 free base, PF-06651600 free bas, EX-A2613, example 5 [WO2015083028], compound 11 [PMID: 28139931], 1-[(2S,5R)-2-methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-1-piperidyl]prop-2-en-1-one

Safety & hazard information (GHS)

Health hazard

Signal word: Warning

Hazard statements

H361Suspected of damaging fertility or the unborn child

Precautionary statements: P203, P280, P318, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ritlecitinib?

The CAS Registry Number of Ritlecitinib is 1792180-81-4. It is also known as 1-[(2S,5R)-2-Methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-1-piperidinyl]-2-propen-1-one, Litfulo, 1-((2S,5R)-2-methyl-5-(7H-pyrrolo(2,3-d)pyrimidin-4-ylamino)piperidin-1-yl)prop-2-en-1-one.

What is the molecular formula and molecular weight of Ritlecitinib?

Ritlecitinib has the molecular formula C15H19N5O and a molecular weight of 285.34 g/mol. Its IUPAC name is 1-[(2S,5R)-2-methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)piperidin-1-yl]prop-2-en-1-one.

What is Ritlecitinib used for?

Ritlecitinib is supplied as a characterised reference material related to Ritlecitinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ritlecitinib can I order?

We supply Ritlecitinib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ritlecitinib?

Yes. Every lot of Ritlecitinib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ritlecitinib be shipped internationally?

Yes. Ritlecitinib is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.