N-Desmethyl Rosuvastatin Lactone

Name: N-Desmethyl Rosuvastatin Lactone
Brand: Vaqora Chemicals
SKU: VQ-035553

About N-Desmethyl Rosuvastatin Lactone

Listed under CAS 1797419-58-9, N-Desmethyl Rosuvastatin Lactone is a metabolite or degradation product of Rosuvastatin available from Vaqora Chemicals. With the molecular formula C21H24FN3O5S, it has a molar mass of 449.5 g/mol. It is also known as Rosuvastatin N-Desmethyl Lactone or N-Desmethyl Rosuvastatin Lactone (Free Base).

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Rosuvastatin, as well as in QC testing and ANDA/DMF documentation. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, N-Desmethyl Rosuvastatin Lactone is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Rosuvastatin

View every impurity, metabolite and intermediate we list for Rosuvastatin.

Rosuvastatin impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Desmethyl Rosuvastatin Lactone
Catalogue No.	VQ-035553
CAS Number	1797419-58-9
IUPAC name	N-[4-(4-fluorophenyl)-5-[(E)-2-[(2S,4R)-4-hydroxy-6-oxooxan-2-yl]ethenyl]-6-propan-2-ylpyrimidin-2-yl]methanesulfonamide
Molecular formula	C₂₁H₂₄FN₃O₅S
Molecular weight	449.5 g/mol
Exact mass	449.1421
Grade	Reference Standard
HSN code	38229090
InChIKey	WSCHZXKSCWERQN-GUFYHEMZSA-N
SMILES	CC(C)C1=NC(=NC(=C1/C=C/[C@@H]2C[C@H](CC(=O)O2)O)C3=CC=C(C=C3)F)NS(=O)(=O)C
PubChem CID	71273139

Physical properties
Physical form	Solid
LogP (XLogP3)	2.2
H-bond donors / acceptors	2 / 9
TPSA	127 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Desmethyl Rosuvastatin Lactone?

The CAS Registry Number of N-Desmethyl Rosuvastatin Lactone is 1797419-58-9. It is also known as Rosuvastatin N-Desmethyl Lactone, N-Desmethyl Rosuvastatin Lactone (Free Base).

What is the molecular formula and molecular weight of N-Desmethyl Rosuvastatin Lactone?

N-Desmethyl Rosuvastatin Lactone has the molecular formula C21H24FN3O5S and a molecular weight of 449.5 g/mol. Its IUPAC name is N-[4-(4-fluorophenyl)-5-[(E)-2-[(2S,4R)-4-hydroxy-6-oxooxan-2-yl]ethenyl]-6-propan-2-ylpyrimidin-2-yl]methanesulfonamide.

What is N-Desmethyl Rosuvastatin Lactone used for?

N-Desmethyl Rosuvastatin Lactone is supplied as a characterised reference material related to Rosuvastatin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Desmethyl Rosuvastatin Lactone can I order?

We supply N-Desmethyl Rosuvastatin Lactone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Desmethyl Rosuvastatin Lactone?

Yes. Every lot of N-Desmethyl Rosuvastatin Lactone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Desmethyl Rosuvastatin Lactone be shipped internationally?

Yes. We export N-Desmethyl Rosuvastatin Lactone worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.