Lasofoxifene

About Lasofoxifene

Lasofoxifene is a high-purity reference standard of Lasofoxifene carrying the CAS registry number 180916-16-9. The compound has the formula C28H31NO2, corresponding to a molecular weight of 413.5 g/mol. Its systematic (IUPAC) name is (5R,6S)-6-phenyl-5-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-5,6,7,8-tetrahydronaphthalen-2-ol. Common synonyms include rac-Lasofoxifene.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

As a reference sample of Lasofoxifene, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Lasofoxifene in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Lasofoxifene

View every impurity, metabolite and intermediate we list for Lasofoxifene.

Lasofoxifene impurities

Specifications & identifiers

Chemical identifiers
Product name	Lasofoxifene
Catalogue No.	VQ-043504
CAS Number	180916-16-9
IUPAC name	(5R,6S)-6-phenyl-5-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-5,6,7,8-tetrahydronaphthalen-2-ol
Molecular formula	C₂₈H₃₁NO₂
Molecular weight	413.5 g/mol
Exact mass	413.2355
Grade	Reference Standard
HSN code	38229090
InChIKey	GXESHMAMLJKROZ-IAPPQJPRSA-N
SMILES	C1CCN(C1)CCOC2=CC=C(C=C2)[C@H]3[C@H](CCC4=C3C=CC(=C4)O)C5=CC=CC=C5
PubChem CID	216416

Physical properties
Physical form	Solid
LogP (XLogP3)	6.1
H-bond donors / acceptors	1 / 3
TPSA	32.7 Å²
Synonyms	(5R,6S)-6-phenyl-5-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,6,7,8-tetrahydronaphthalen-2-ol, (-)-cis-5,6,7,8-Tetrahydro-6-phenyl-5-(p-(2-(1-pyrrolidinyl)ethoxy)phenyl)-2-naphthol, (5R,6S)-6-phenyl-5-{4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}-5,6,7,8-tetrahydronaphthalen-2-ol, rac-Lasofoxifene, (1R,2S)-2-phenyl-1-[4-(2-pyrrolidin-1-ylethoxy)phenyl]tetralin-6-ol, (-)-cis-5,6,7,8-Tetrahydro-6-phenyl-5-(p-(2-(1-pyrrolidinyl)ethoxy)phenyl)-2-naphthol., cis-6-Phenvl-5-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-5,6,7,8-tetrahydronaphthalene-2-ol, cis-6-phenyl-5-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-5,6,7,8-tetrahydronaphthalen-2-ol, cis-6-Phenyl-5-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-5,6,7,8-tetrahydronaphthalene-2-ol, cis-6Phenyl-5-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-5,6,7,8-tetrahydronaphthalene-2-ol

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Lasofoxifene?

The CAS Registry Number of Lasofoxifene is 180916-16-9. It is also known as (5R,6S)-6-phenyl-5-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,6,7,8-tetrahydronaphthalen-2-ol, (-)-cis-5,6,7,8-Tetrahydro-6-phenyl-5-(p-(2-(1-pyrrolidinyl)ethoxy)phenyl)-2-naphthol, (5R,6S)-6-phenyl-5-{4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}-5,6,7,8-tetrahydronaphthalen-2-ol.

What is the molecular formula and molecular weight of Lasofoxifene?

Lasofoxifene has the molecular formula C28H31NO2 and a molecular weight of 413.5 g/mol. Its IUPAC name is (5R,6S)-6-phenyl-5-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-5,6,7,8-tetrahydronaphthalen-2-ol.

What is Lasofoxifene used for?

Lasofoxifene is supplied as a characterised reference material related to Lasofoxifene. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Lasofoxifene can I order?

We supply Lasofoxifene in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Lasofoxifene?

Yes. Every lot of Lasofoxifene is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Lasofoxifene be shipped internationally?

Yes. We export Lasofoxifene worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.