N-Desmethyl Vinblastine

Name: N-Desmethyl Vinblastine
Brand: Vaqora Chemicals
SKU: VQ-028713

About N-Desmethyl Vinblastine

N-Desmethyl Vinblastine (CAS 18172-50-4) is a metabolite or degradation product of Vincristine offered by Vaqora Chemicals. The compound has the formula C45H56N4O9, corresponding to a molecular weight of 796.9 g/mol. Alternative names: N-Demethylvinblastine and 1-Demethylvincaleukoblastine.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

Analytical teams use this compound to identify metabolites and degradants of Vincristine, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies N-Desmethyl Vinblastine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Vincristine

View every impurity, metabolite and intermediate we list for Vincristine.

Vincristine impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Desmethyl Vinblastine
Catalogue No.	VQ-028713
CAS Number	18172-50-4
IUPAC name	methyl (1S,9R,10S,11R,12R,19R)-11-acetyloxy-12-ethyl-4-[(13S,15R,17S)-17-ethyl-17-hydroxy-13-methoxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]-10-hydroxy-5-methoxy-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate
Molecular formula	C₄₅H₅₆N₄O₉
Molecular weight	796.9 g/mol
Exact mass	796.4047
Grade	Reference Standard
HSN code	38229090
InChIKey	OBEIXXHHUOSBLA-UQUCNHJPSA-N
SMILES	CC[C@@]1(C[C@H]2C[C@@](C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)[C@]78CCN9[C@H]7[C@@](C=CC9)([C@H]([C@@]([C@@H]8N6)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)O
PubChem CID	56841098

Physical properties
Physical form	Solid
LogP (XLogP3)	3.6
H-bond donors / acceptors	4 / 12
TPSA	163 Å²
Synonyms	N-Demethylvinblastine, 1-Demethylvincaleukoblastine, Vincaleukoblastine, 1-demethyl-, N-Deformylvincristine, N-Deformylleurocristine, N-Demethylvincaleukoblastine

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Desmethyl Vinblastine?

The CAS Registry Number of N-Desmethyl Vinblastine is 18172-50-4. It is also known as N-Demethylvinblastine, 1-Demethylvincaleukoblastine, Vincaleukoblastine, 1-demethyl-.

What is the molecular formula and molecular weight of N-Desmethyl Vinblastine?

N-Desmethyl Vinblastine has the molecular formula C45H56N4O9 and a molecular weight of 796.9 g/mol.

What is N-Desmethyl Vinblastine used for?

N-Desmethyl Vinblastine is supplied as a characterised reference material related to Vincristine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Desmethyl Vinblastine can I order?

We supply N-Desmethyl Vinblastine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Desmethyl Vinblastine?

Yes. Every lot of N-Desmethyl Vinblastine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Desmethyl Vinblastine be shipped internationally?

Yes. We export N-Desmethyl Vinblastine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.