Erlotinib O-Desmethyl Isomer Metabolite

Name: Erlotinib O-Desmethyl Isomer Metabolite
Brand: Vaqora Chemicals
SKU: VQ-007166

About Erlotinib O-Desmethyl Isomer Metabolite

Erlotinib O-Desmethyl Isomer Metabolite is a metabolite or degradation product of Erlotinib carrying the CAS registry number 183320-29-8. The compound has the formula C21H21N3O4, corresponding to a molecular weight of 379.4 g/mol. The IUPAC name is 2-[4-(3-ethynylanilino)-6-(2-methoxyethoxy)quinazolin-7-yl]oxyethanol. Alternative names: 7-(2'-Desmethyl) Erlotinib and Erlotinib Impurity 4.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Analytical teams use this compound to identify metabolites and degradants of Erlotinib, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Erlotinib O-Desmethyl Isomer Metabolite in 10 mg, 25 mg and 50 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. Stock is available for quick dispatch.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Erlotinib

View every impurity, metabolite and intermediate we list for Erlotinib.

Erlotinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Erlotinib O-Desmethyl Isomer Metabolite
Catalogue No.	VQ-007166
CAS Number	183320-29-8
IUPAC name	2-[4-(3-ethynylanilino)-6-(2-methoxyethoxy)quinazolin-7-yl]oxyethanol
Molecular formula	C₂₁H₂₁N₃O₄
Molecular weight	379.4 g/mol
Exact mass	379.1532
Grade	Reference Standard
HSN code	38229090
InChIKey	MTLKTHNRZJKPRP-UHFFFAOYSA-N
SMILES	COCCOC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=CC(=C3)C#C)OCCO
PubChem CID	16045730

Physical properties
Physical form	Solid
LogP (XLogP3)	2.8
H-bond donors / acceptors	2 / 7
TPSA	85.7 Å²
Synonyms	2-((4-((3-ethynylphenyl)amino)-6-(2-methoxyethoxy)quinazolin-7-yl)oxy)ethanol, 7-(2'-Desmethyl) Erlotinib, Erlotinib Impurity 4, OSI 413, Erlotinib 7-O-Desmethyl Metabolite, OSI-413, Erlotinib metabolite M13, 2-(4-(3-Ethynylanilino)-6-(2-methoxyethoxy)quinazolin-7-yl)oxyethanol, Ethanol, 2-((4-((3-ethynylphenyl)amino)-6-(2-methoxyethoxy)-7-quinazolinyl)oxy)-, OSI-413 (free base), 2-((4-((3-Ethynylphenyl)amino)-6-(2-methoxyethoxy)quinazolin-7-yl)oxy)ethan-1-ol, Erlotinib Hydrochloride Impurity A

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Erlotinib O-Desmethyl Isomer Metabolite?

The CAS Registry Number of Erlotinib O-Desmethyl Isomer Metabolite is 183320-29-8. It is also known as 2-((4-((3-ethynylphenyl)amino)-6-(2-methoxyethoxy)quinazolin-7-yl)oxy)ethanol, 7-(2'-Desmethyl) Erlotinib, Erlotinib Impurity 4.

What is the molecular formula and molecular weight of Erlotinib O-Desmethyl Isomer Metabolite?

Erlotinib O-Desmethyl Isomer Metabolite has the molecular formula C21H21N3O4 and a molecular weight of 379.4 g/mol. Its IUPAC name is 2-[4-(3-ethynylanilino)-6-(2-methoxyethoxy)quinazolin-7-yl]oxyethanol.

What is Erlotinib O-Desmethyl Isomer Metabolite used for?

Erlotinib O-Desmethyl Isomer Metabolite is supplied as a characterised reference material related to Erlotinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Erlotinib O-Desmethyl Isomer Metabolite can I order?

We supply Erlotinib O-Desmethyl Isomer Metabolite in Reference Standard grade, in 10 mg, 25 mg, 50 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Erlotinib O-Desmethyl Isomer Metabolite?

Yes. Every lot of Erlotinib O-Desmethyl Isomer Metabolite is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Erlotinib O-Desmethyl Isomer Metabolite be shipped internationally?

Yes. We export Erlotinib O-Desmethyl Isomer Metabolite worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.