Erlotinib Didesmethyl Impurity

Name: Erlotinib Didesmethyl Impurity
Brand: Vaqora Chemicals
SKU: VQ-007163

About Erlotinib Didesmethyl Impurity

Erlotinib Didesmethyl Impurity (CAS 183321-84-8) is a metabolite or degradation product of Erlotinib offered by Vaqora Chemicals. The compound has the formula C20H19N3O4, corresponding to a molecular weight of 365.4 g/mol. Its systematic (IUPAC) name is 2-[4-(3-ethynylanilino)-7-(2-hydroxyethoxy)quinazolin-6-yl]oxyethanol. Alternative names: Didesmethyl Erlotinib and Erlotinib metabolite M12.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants of Erlotinib, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Erlotinib

View every impurity, metabolite and intermediate we list for Erlotinib.

Erlotinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Erlotinib Didesmethyl Impurity
Catalogue No.	VQ-007163
CAS Number	183321-84-8
IUPAC name	2-[4-(3-ethynylanilino)-7-(2-hydroxyethoxy)quinazolin-6-yl]oxyethanol
Molecular formula	C₂₀H₁₉N₃O₄
Molecular weight	365.4 g/mol
Exact mass	365.1376
Grade	Reference Standard
HSN code	38229090
InChIKey	YWSAEKIQJPQSDJ-UHFFFAOYSA-N
SMILES	C#CC1=CC(=CC=C1)NC2=NC=NC3=CC(=C(C=C32)OCCO)OCCO
PubChem CID	16045656

Physical properties
Physical form	Solid
LogP (XLogP3)	2.2
H-bond donors / acceptors	3 / 7
TPSA	96.7 Å²
Synonyms	2,2'-((4-((3-ethynylphenyl)amino)quinazoline-6,7-diyl)bis(oxy))diethanol, 2,2'-((4-((3-Ethynylphenyl)amino)quinazoline-6,7-diyl)bis(oxy))bis(ethan-1-ol), 2,2'-[[4-[(3-Ethynylphenyl)amino]-6,7-quinazolinediyl]bis(oxy)]bis-ethanol, Didesmethyl Erlotinib, 4-[(3-Ethynylphenyl)amino]-6,7-bis(2-hydroxyethoxy)quinazoline, Erlotinib metabolite M12, OSI-943, Ethanol, 2,2'-[[4-[(3-ethynylphenyl)amino]-6,7-quinazolinediyl]bis(oxy)]bis-, 2-(4-(3-Ethynylanilino)-7-(2-hydroxyethoxy)quinazolin-6-yl)oxyethanol, Ethanol, 2,2'-((4-((3-ethynylphenyl)amino)-6,7-quinazolinediyl)bis(oxy))bis-, Ethanol, 2-((4-((3-ethynylphenyl)amino)-6-(2-hydroxyethoxy)-7-quinazolinyl)oxy)-, 2-({4-[(3-ethynylphenyl)amino]-6-(2-hydroxyethoxy)quinazolin-7-yl}oxy)ethan-1-ol

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Erlotinib Didesmethyl Impurity?

The CAS Registry Number of Erlotinib Didesmethyl Impurity is 183321-84-8. It is also known as 2,2'-((4-((3-ethynylphenyl)amino)quinazoline-6,7-diyl)bis(oxy))diethanol, 2,2'-((4-((3-Ethynylphenyl)amino)quinazoline-6,7-diyl)bis(oxy))bis(ethan-1-ol), 2,2'-[[4-[(3-Ethynylphenyl)amino]-6,7-quinazolinediyl]bis(oxy)]bis-ethanol.

What is the molecular formula and molecular weight of Erlotinib Didesmethyl Impurity?

Erlotinib Didesmethyl Impurity has the molecular formula C20H19N3O4 and a molecular weight of 365.4 g/mol. Its IUPAC name is 2-[4-(3-ethynylanilino)-7-(2-hydroxyethoxy)quinazolin-6-yl]oxyethanol.

What is Erlotinib Didesmethyl Impurity used for?

Erlotinib Didesmethyl Impurity is supplied as a characterised reference material related to Erlotinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Erlotinib Didesmethyl Impurity can I order?

We supply Erlotinib Didesmethyl Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Erlotinib Didesmethyl Impurity?

Yes. Every lot of Erlotinib Didesmethyl Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Erlotinib Didesmethyl Impurity be shipped internationally?

Yes. We export Erlotinib Didesmethyl Impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.