Erlotinib Chloro Impurity (Freebase)

Name: Erlotinib Chloro Impurity (Freebase)
Brand: Vaqora Chemicals
SKU: VQ-004911

About Erlotinib Chloro Impurity (Freebase)

Listed under CAS 183322-18-1, Erlotinib Chloro Impurity (Freebase) is an impurity of Erlotinib available from Vaqora Chemicals. Its molecular formula is C14H17ClN2O4 and its molecular weight is 312.75 g/mol. The IUPAC name is 4-chloro-6,7-bis(2-methoxyethoxy)quinazoline. Alternative names: Erlotinib Chloro Impurity and 4-Chloro-6,7-di(2-methoxyethoxy) quinazoline.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Erlotinib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Erlotinib Chloro Impurity (Freebase) in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Erlotinib

View every impurity, metabolite and intermediate we list for Erlotinib.

Erlotinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Erlotinib Chloro Impurity (Freebase)
Catalogue No.	VQ-004911
CAS Number	183322-18-1
Other CAS	179688-13-2
IUPAC name	4-chloro-6,7-bis(2-methoxyethoxy)quinazoline
Molecular formula	C₁₄H₁₇ClN₂O₄
Molecular weight	312.75 g/mol
Exact mass	312.0877
Grade	Reference Standard
HSN code	38229090
InChIKey	ZPJLDMNVDPGZIU-UHFFFAOYSA-N
SMILES	COCCOC1=C(C=C2C(=C1)C(=NC=N2)Cl)OCCOC
PubChem CID	11289942

Physical properties
Physical form	Solid
LogP (XLogP3)	2.1
H-bond donors / acceptors	0 / 6
TPSA	62.7 Å²
Synonyms	Erlotinib Chloro Impurity, 4-Chloro-6,7-di(2-methoxyethoxy) quinazoline, 6,7-Bis(2-methoxyethoxy)-4-chloroquinazoline, Quinazoline, 4-chloro-6,7-bis(2-methoxyethoxy)-, 4-Chloro-6,7-Bis-(2-methoxyethoxy)-4(3H)-quinazoline, Erlotinib Impurity 8, 4-Chloro-6,7-(2-methoxyethoxy)-quinazoline, 4-Chloro-6,7-bis-(2-methoxy-ethoxy)-quinazoline, 4-chloro-6,7-bis(2-methoxyethoxy) quinazoline, 4-chloro-6,7-bis(2-methoxyethoxy)-quinazoline, 4-chloro-6,7-bis-(2-methoxyethoxy)quinazoline, 4-chloro-6,7-bis-(2-methoxyethoxy)-quinazoline

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H318Causes serious eye damage

Precautionary statements: P264, P264 + P265, P270, P280, P301 + P317, P305 + P354 + P338, P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Erlotinib Chloro Impurity (Freebase)?

The CAS Registry Number of Erlotinib Chloro Impurity (Freebase) is 183322-18-1. It is also known as Erlotinib Chloro Impurity, 4-Chloro-6,7-di(2-methoxyethoxy) quinazoline, 6,7-Bis(2-methoxyethoxy)-4-chloroquinazoline.

What is the molecular formula and molecular weight of Erlotinib Chloro Impurity (Freebase)?

Erlotinib Chloro Impurity (Freebase) has the molecular formula C14H17ClN2O4 and a molecular weight of 312.75 g/mol. Its IUPAC name is 4-chloro-6,7-bis(2-methoxyethoxy)quinazoline.

What is Erlotinib Chloro Impurity (Freebase) used for?

Erlotinib Chloro Impurity (Freebase) is supplied as a characterised reference material related to Erlotinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Erlotinib Chloro Impurity (Freebase) can I order?

We supply Erlotinib Chloro Impurity (Freebase) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Erlotinib Chloro Impurity (Freebase)?

Yes. Every lot of Erlotinib Chloro Impurity (Freebase) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Erlotinib Chloro Impurity (Freebase) be shipped internationally?

Yes. Erlotinib Chloro Impurity (Freebase) is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.