(E)-4-(2,4,5-Trifluorophenyl)but-2-enoic acid 1840966-95-1

About (E)-4-(2,4,5-Trifluorophenyl)but-2-enoic acid

(E)-4-(2,4,5-Trifluorophenyl)but-2-enoic acid is an impurity of Sitagliptin carrying the CAS registry number 1840966-95-1. Its molecular formula is C10H7F3O2 and its molecular weight is 216.16 g/mol. It is also known as 4-(2,4,5-trifluorophenyl)but-2-enoic acid.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

As a characterised impurity of Sitagliptin, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer (E)-4-(2,4,5-Trifluorophenyl)but-2-enoic acid in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Sitagliptin

View every impurity, metabolite and intermediate we list for Sitagliptin.

Sitagliptin impurities

Specifications & identifiers

Chemical identifiers
Product name	(E)-4-(2,4,5-Trifluorophenyl)but-2-enoic acid
Catalogue No.	VQ-042202
CAS Number	1840966-95-1
IUPAC name	(E)-4-(2,4,5-trifluorophenyl)but-2-enoic acid
Molecular formula	C₁₀H₇F₃O₂
Molecular weight	216.16 g/mol
Exact mass	216.0398
Grade	Reference Standard
HSN code	38229090
InChIKey	LTQSXIYFLNHNDE-HNQUOIGGSA-N
SMILES	C1=C(C(=CC(=C1F)F)F)C/C=C/C(=O)O
PubChem CID	71077810

Physical properties
Physical form	Solid
LogP (XLogP3)	2.5
H-bond donors / acceptors	1 / 5
TPSA	37.3 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (E)-4-(2,4,5-Trifluorophenyl)but-2-enoic acid?

The CAS Registry Number of (E)-4-(2,4,5-Trifluorophenyl)but-2-enoic acid is 1840966-95-1. It is also known as 4-(2,4,5-trifluorophenyl)but-2-enoic acid.

What is the molecular formula and molecular weight of (E)-4-(2,4,5-Trifluorophenyl)but-2-enoic acid?

(E)-4-(2,4,5-Trifluorophenyl)but-2-enoic acid has the molecular formula C10H7F3O2 and a molecular weight of 216.16 g/mol. Its IUPAC name is (E)-4-(2,4,5-trifluorophenyl)but-2-enoic acid.

What is (E)-4-(2,4,5-Trifluorophenyl)but-2-enoic acid used for?

(E)-4-(2,4,5-Trifluorophenyl)but-2-enoic acid is supplied as a characterised reference material related to Sitagliptin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (E)-4-(2,4,5-Trifluorophenyl)but-2-enoic acid can I order?

We supply (E)-4-(2,4,5-Trifluorophenyl)but-2-enoic acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (E)-4-(2,4,5-Trifluorophenyl)but-2-enoic acid?

Yes. Every lot of (E)-4-(2,4,5-Trifluorophenyl)but-2-enoic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (E)-4-(2,4,5-Trifluorophenyl)but-2-enoic acid be shipped internationally?

Yes. We export (E)-4-(2,4,5-Trifluorophenyl)but-2-enoic acid worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.