8-Benzoyl-1,4-dihydrocinnolin-3(2H)-one

Name: 8-Benzoyl-1,4-dihydrocinnolin-3(2H)-one
Brand: Vaqora Chemicals
SKU: VQ-038589

About 8-Benzoyl-1,4-dihydrocinnolin-3(2H)-one

Listed under CAS 1881270-49-0, 8-Benzoyl-1,4-dihydrocinnolin-3(2H)-one is an impurity of Nepafenac available from Vaqora Chemicals. The compound has the formula C15H12N2O2, corresponding to a molecular weight of 252.27 g/mol. Systematically, it is named 8-benzoyl-2,4-dihydro-1H-cinnolin-3-one. Alternative names: 8-benzoyl-1,4-dihydro-3(2H)-Cinnolinone.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Nepafenac to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 8-Benzoyl-1,4-dihydrocinnolin-3(2H)-one is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Nepafenac

View every impurity, metabolite and intermediate we list for Nepafenac.

Nepafenac impurities

Specifications & identifiers

Chemical identifiers
Product name	8-Benzoyl-1,4-dihydrocinnolin-3(2H)-one
Catalogue No.	VQ-038589
CAS Number	1881270-49-0
IUPAC name	8-benzoyl-2,4-dihydro-1H-cinnolin-3-one
Molecular formula	C₁₅H₁₂N₂O₂
Molecular weight	252.27 g/mol
Exact mass	252.0899
Grade	Reference Standard
HSN code	38229090
InChIKey	COSMGALUGGCMFZ-UHFFFAOYSA-N
SMILES	C1C2=C(C(=CC=C2)C(=O)C3=CC=CC=C3)NNC1=O
PubChem CID	177831888

Physical properties
Physical form	Solid
LogP (XLogP3)	2.4
H-bond donors / acceptors	2 / 3
TPSA	58.2 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 8-Benzoyl-1,4-dihydrocinnolin-3(2H)-one?

The CAS Registry Number of 8-Benzoyl-1,4-dihydrocinnolin-3(2H)-one is 1881270-49-0. It is also known as 8-benzoyl-1,4-dihydro-3(2H)-Cinnolinone.

What is the molecular formula and molecular weight of 8-Benzoyl-1,4-dihydrocinnolin-3(2H)-one?

8-Benzoyl-1,4-dihydrocinnolin-3(2H)-one has the molecular formula C15H12N2O2 and a molecular weight of 252.27 g/mol. Its IUPAC name is 8-benzoyl-2,4-dihydro-1H-cinnolin-3-one.

What is 8-Benzoyl-1,4-dihydrocinnolin-3(2H)-one used for?

8-Benzoyl-1,4-dihydrocinnolin-3(2H)-one is supplied as a characterised reference material related to Nepafenac. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 8-Benzoyl-1,4-dihydrocinnolin-3(2H)-one can I order?

We supply 8-Benzoyl-1,4-dihydrocinnolin-3(2H)-one in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 8-Benzoyl-1,4-dihydrocinnolin-3(2H)-one?

Yes. Every lot of 8-Benzoyl-1,4-dihydrocinnolin-3(2H)-one is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 8-Benzoyl-1,4-dihydrocinnolin-3(2H)-one be shipped internationally?

Yes. We export 8-Benzoyl-1,4-dihydrocinnolin-3(2H)-one worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.