O-Tert-Butyl-L-serine

Name: O-Tert-Butyl-L-serine
Brand: Vaqora Chemicals
SKU: VQ-040554

About O-Tert-Butyl-L-serine

O-Tert-Butyl-L-serine (CAS 18822-58-7) is a process intermediate or related compound of Allopurinol offered by Vaqora Chemicals. With the molecular formula C7H15NO3, it has a molar mass of 161.2 g/mol. Systematically, it is named (2S)-2-amino-3-[(2-methylpropan-2-yl)oxy]propanoic acid. It is also known as H-Ser(tBu)-OH or (2S)-2-amino-3-(tert-butoxy)propanoic acid.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Process chemists and analysts use it when developing synthetic routes to Allopurinol, tracking process-related impurities and validating analytical methods. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer O-Tert-Butyl-L-serine in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development
Fine chemical synthesis

Industries

Related to Allopurinol

View every impurity, metabolite and intermediate we list for Allopurinol.

Allopurinol impurities

Specifications & identifiers

Chemical identifiers
Product name	O-Tert-Butyl-L-serine
Catalogue No.	VQ-040554
CAS Number	18822-58-7
IUPAC name	(2S)-2-amino-3-[(2-methylpropan-2-yl)oxy]propanoic acid
Molecular formula	C₇H₁₅NO₃
Molecular weight	161.2 g/mol
Exact mass	161.1052
InChIKey	DDCPKNYKNWXULB-YFKPBYRVSA-N
SMILES	CC(C)(C)OC[C@@H](C(=O)O)N
PubChem CID	7004940

Physical properties
Physical form	Solid
LogP (XLogP3)	-2.5
H-bond donors / acceptors	2 / 4
TPSA	72.6 Å²
Synonyms	H-Ser(tBu)-OH, (2S)-2-amino-3-(tert-butoxy)propanoic acid, O-(1,1-Dimethylethyl)-L-serine, L-Serine, O-(1,1-dimethylethyl)-, (S)-2-Amino-3-(tert-butoxy)propanoic acid, o-tert-butylserine, O-t-BUTYL-L-SERINE, Serine tert-butyl ether, (2S)-2-azaniumyl-3-[(2-methylpropan-2-yl)oxy]propanoate, (2s)-2-amino-3-((2-methylpropan-2-yl)oxy)propanoic acid, L-Ser(tBu)-OH

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of O-Tert-Butyl-L-serine?

The CAS Registry Number of O-Tert-Butyl-L-serine is 18822-58-7. It is also known as H-Ser(tBu)-OH, (2S)-2-amino-3-(tert-butoxy)propanoic acid, O-(1,1-Dimethylethyl)-L-serine.

What is the molecular formula and molecular weight of O-Tert-Butyl-L-serine?

O-Tert-Butyl-L-serine has the molecular formula C7H15NO3 and a molecular weight of 161.2 g/mol. Its IUPAC name is (2S)-2-amino-3-[(2-methylpropan-2-yl)oxy]propanoic acid.

What is O-Tert-Butyl-L-serine used for?

O-Tert-Butyl-L-serine is supplied as a characterised reference material related to Allopurinol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of O-Tert-Butyl-L-serine can I order?

We supply O-Tert-Butyl-L-serine, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with O-Tert-Butyl-L-serine?

Yes. Every lot of O-Tert-Butyl-L-serine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can O-Tert-Butyl-L-serine be shipped internationally?

Yes. O-Tert-Butyl-L-serine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.