1-tert-Butoxy-4-chlorobenzene

Name: 1-tert-Butoxy-4-chlorobenzene
Brand: Vaqora Chemicals
SKU: VQ-051392

About 1-tert-Butoxy-4-chlorobenzene

1-tert-Butoxy-4-chlorobenzene (CAS 18995-35-2) is a process intermediate or related compound of Metoprolol offered by Vaqora Chemicals. The compound has the formula C10H13ClO, corresponding to a molecular weight of 184.66 g/mol. Systematically, it is named 1-chloro-4-[(2-methylpropan-2-yl)oxy]benzene. Alternative names: 4-tert-Butoxychlorobenzene and 1-Chloro-4-tert-butoxybenzene.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

It is a process intermediate or related compound in the synthesis of Metoprolol, useful for route development, impurity fate-and-purge studies and analytical method development. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Metoprolol

View every impurity, metabolite and intermediate we list for Metoprolol.

Metoprolol impurities

Specifications & identifiers

Chemical identifiers
Product name	1-tert-Butoxy-4-chlorobenzene
Catalogue No.	VQ-051392
CAS Number	18995-35-2
IUPAC name	1-chloro-4-[(2-methylpropan-2-yl)oxy]benzene
Molecular formula	C₁₀H₁₃ClO
Molecular weight	184.66 g/mol
Exact mass	184.0655
InChIKey	NEJWTQIEQDHWTR-UHFFFAOYSA-N
SMILES	CC(C)(C)OC1=CC=C(C=C1)Cl
PubChem CID	140458

Physical properties
Physical form	Solid
LogP (XLogP3)	3.8
H-bond donors / acceptors	0 / 1
TPSA	9.2 Å²
Synonyms	4-tert-Butoxychlorobenzene, 1-Chloro-4-tert-butoxybenzene, 4-chloro-1-tert-butoxybenzene, Benzene, 1-chloro-4-(1,1-dimethylethoxy)-, tert-Butyl 4-Chlorophenyl Ether, 4-t-butoxychlorobenzene, 4-t-butoxy chlorobenzene, 4-tert-butoxyphenyl chloride, p-tert-butoxyphenyl chloride, 4-tert-Butoxy-1-chlorobenzene

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1-tert-Butoxy-4-chlorobenzene?

The CAS Registry Number of 1-tert-Butoxy-4-chlorobenzene is 18995-35-2. It is also known as 4-tert-Butoxychlorobenzene, 1-Chloro-4-tert-butoxybenzene, 4-chloro-1-tert-butoxybenzene.

What is the molecular formula and molecular weight of 1-tert-Butoxy-4-chlorobenzene?

1-tert-Butoxy-4-chlorobenzene has the molecular formula C10H13ClO and a molecular weight of 184.66 g/mol. Its IUPAC name is 1-chloro-4-[(2-methylpropan-2-yl)oxy]benzene.

What is 1-tert-Butoxy-4-chlorobenzene used for?

1-tert-Butoxy-4-chlorobenzene is supplied as a characterised reference material related to Metoprolol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1-tert-Butoxy-4-chlorobenzene can I order?

We supply 1-tert-Butoxy-4-chlorobenzene, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1-tert-Butoxy-4-chlorobenzene?

Yes. Every lot of 1-tert-Butoxy-4-chlorobenzene is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1-tert-Butoxy-4-chlorobenzene be shipped internationally?

Yes. We export 1-tert-Butoxy-4-chlorobenzene worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.