(S)-Tetrahydro-a-(1-methylethyl)-2-oxo-1(2H)-… 192725-50-1

About (S)-Tetrahydro-a-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetic acid

(S)-Tetrahydro-a-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetic acid is a process intermediate or related compound of Lopinavir carrying the CAS registry number 192725-50-1. Formula C9H16N2O3, molecular weight 200.23 g/mol. The IUPAC name is (2S)-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanoic acid.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

It is a process intermediate or related compound in the synthesis of Lopinavir, useful for route development, impurity fate-and-purge studies and analytical method development. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, (S)-Tetrahydro-a-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetic acid is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development
Fine chemical synthesis

Industries

Related to Lopinavir

View every impurity, metabolite and intermediate we list for Lopinavir.

Lopinavir impurities

Specifications & identifiers

Chemical identifiers
Product name	(S)-Tetrahydro-a-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetic acid
Catalogue No.	VQ-038119
CAS Number	192725-50-1
IUPAC name	(2S)-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanoic acid
Molecular formula	C₉H₁₆N₂O₃
Molecular weight	200.23 g/mol
Exact mass	200.1161
HSN code	2933
InChIKey	AFGBRTKUTJQHIP-ZETCQYMHSA-N
SMILES	CC(C)[C@@H](C(=O)O)N1CCCNC1=O
PubChem CID	10910533

Physical properties
Physical form	Solid
LogP (XLogP3)	0.6
H-bond donors / acceptors	2 / 3
TPSA	69.6 Å²
Synonyms	(S)-3-methyl-2-(2-oxotetrahydropyrimidine-1-yl)butyric acid, (S)-3-Methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)butanoic acid, (2S)-(1-Tetrahydropyramid-2-one)-3-methylbutanoic acid, (2S)-3-Methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)butanoic acid, (s)-tetrahydro-alpha-(1-methylethyl)-2-oxo-1(2h)-pyrimidineacetic acid, 1(2H)-Pyrimidineacetic acid, tetrahydro-alpha-(1-methylethyl)-2-oxo-, (alphaS)-, 1(2H)-Pyrimidineacetic acid, tetrahydro-a-(1-methylethyl)-2-oxo-, (aS)-, (2S)-3-methyl-2-(2-oxidanylidene-1,3-diazinan-1-yl)butanoic acid, (S)-3-Methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)butanoicacid, 1(2H)-Pyrimidineacetic acid, tetrahydro-, A-(1-methylethyl)-2-oxo-, (, AS)-

Safety & hazard information (GHS)

Corrosive

Signal word: Danger

Hazard statements

H318Causes serious eye damage

Precautionary statements: P264 + P265, P280, P305 + P354 + P338, P317

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (S)-Tetrahydro-a-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetic acid?

The CAS Registry Number of (S)-Tetrahydro-a-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetic acid is 192725-50-1. It is also known as (S)-3-methyl-2-(2-oxotetrahydropyrimidine-1-yl)butyric acid, (S)-3-Methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)butanoic acid, (2S)-(1-Tetrahydropyramid-2-one)-3-methylbutanoic acid.

What is the molecular formula and molecular weight of (S)-Tetrahydro-a-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetic acid?

(S)-Tetrahydro-a-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetic acid has the molecular formula C9H16N2O3 and a molecular weight of 200.23 g/mol. Its IUPAC name is (2S)-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanoic acid.

What is (S)-Tetrahydro-a-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetic acid used for?

(S)-Tetrahydro-a-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetic acid is supplied as a characterised reference material related to Lopinavir. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (S)-Tetrahydro-a-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetic acid can I order?

We supply (S)-Tetrahydro-a-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetic acid, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (S)-Tetrahydro-a-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetic acid?

Yes. Every lot of (S)-Tetrahydro-a-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (S)-Tetrahydro-a-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetic acid be shipped internationally?

Yes. (S)-Tetrahydro-a-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetic acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.